266440

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) ykfI-yeeU/CbtA-CbeA
Location 2041633..2042380 Replicon chromosome
Accession NZ_CP114280
Organism Dickeya lacustris strain LMG30899

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag O1Q98_RS09260 Protein ID WP_102802208.1
Coordinates 2041633..2041953 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag O1Q98_RS09265 Protein ID WP_240632698.1
Coordinates 2041979..2042380 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q98_RS09230 (O1Q98_09235) 2037133..2038182 - 1050 WP_125258126.1 NAD(P)-dependent alcohol dehydrogenase -
O1Q98_RS09235 (O1Q98_09240) 2038343..2039260 + 918 WP_125258125.1 LysR family transcriptional regulator -
O1Q98_RS09240 (O1Q98_09245) 2039611..2040006 - 396 WP_125258124.1 DUF6088 family protein -
O1Q98_RS09245 (O1Q98_09250) 2040043..2040318 - 276 WP_012883161.1 type II toxin-antitoxin system RelE/ParE family toxin -
O1Q98_RS09250 (O1Q98_09255) 2040322..2040570 - 249 WP_012883160.1 ribbon-helix-helix domain-containing protein -
O1Q98_RS09255 (O1Q98_09260) 2040681..2041514 - 834 WP_278143540.1 DUF4942 domain-containing protein -
O1Q98_RS09260 (O1Q98_09265) 2041633..2041953 - 321 WP_102802208.1 TA system toxin CbtA family protein Toxin
O1Q98_RS09265 (O1Q98_09270) 2041979..2042380 - 402 WP_240632698.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
O1Q98_RS09270 (O1Q98_09275) 2042380..2042853 - 474 WP_278143545.1 DNA repair protein RadC -
O1Q98_RS09275 (O1Q98_09280) 2042884..2043705 - 822 WP_278143547.1 DUF932 domain-containing protein -
O1Q98_RS09280 (O1Q98_09285) 2043802..2044668 - 867 WP_033576640.1 GTPase family protein -
O1Q98_RS09285 (O1Q98_09290) 2044802..2045629 - 828 WP_278143551.1 ribbon-helix-helix domain-containing protein -
O1Q98_RS09290 (O1Q98_09295) 2046372..2047001 + 630 WP_278143553.1 inovirus Gp2 family protein -
O1Q98_RS09295 (O1Q98_09300) 2047122..2047334 + 213 WP_125258094.1 AlpA family phage regulatory protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-105)

Antitoxin

(23-121)


Sequences


Toxin        


Download         Length: 107 a.a.        Molecular weight: 11955.60 Da        Isoelectric Point: 5.0757

>T266440 WP_102802208.1 NZ_CP114280:c2041953-2041633 [Dickeya lacustris]
MQTPSPSPAREASSCLSPVNVWQQLLTYLLDKHYGLTLNDTPFCEEAEIQAHLDAGVSLPDAVNFLVERYELVRIDRSGF
SWQEQKPFLNAVDILRARRATGLLKP

Download         Length: 321 bp


Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14603.74 Da        Isoelectric Point: 6.7399

>AT266440 WP_240632698.1 NZ_CP114280:c2042380-2041979 [Dickeya lacustris]
MPFTVIPLTCQEKSTLSLSDALEWGLEHTLKPRFGARLVQEGCHLHFLADRAGVTGTFSATVACHLEHRFPLLVRQLEQK
LVTGELDPRRQQRVTLHDGVLTCEADTLGSAGYVYITIYPTTAATPATAFPSP

Download         Length: 402 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References