266437

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1972125..1972651 Replicon chromosome
Accession NZ_CP114280
Organism Dickeya lacustris strain LMG30899

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag O1Q98_RS08920 Protein ID WP_125258181.1
Coordinates 1972346..1972651 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID E0SK21
Locus tag O1Q98_RS08915 Protein ID WP_012773205.1
Coordinates 1972125..1972343 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q98_RS08885 (O1Q98_08890) 1967266..1968567 + 1302 WP_125258185.1 anaerobic C4-dicarboxylate transporter -
O1Q98_RS08890 (O1Q98_08895) 1968704..1969048 + 345 WP_125258184.1 divalent cation tolerance protein CutA -
O1Q98_RS08895 (O1Q98_08900) 1969024..1970769 + 1746 WP_125258183.1 protein-disulfide reductase DsbD -
O1Q98_RS08900 (O1Q98_08905) 1970889..1971464 + 576 WP_125258182.1 transcriptional regulator -
O1Q98_RS08910 (O1Q98_08915) 1971804..1972032 + 229 Protein_1742 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
O1Q98_RS08915 (O1Q98_08920) 1972125..1972343 + 219 WP_012773205.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
O1Q98_RS08920 (O1Q98_08925) 1972346..1972651 + 306 WP_125258181.1 type II toxin-antitoxin system toxin CcdB Toxin
O1Q98_RS08925 (O1Q98_08930) 1972805..1975177 - 2373 WP_125258180.1 AAA family ATPase -
O1Q98_RS08930 (O1Q98_08935) 1975170..1975889 - 720 WP_125258179.1 hypothetical protein -
O1Q98_RS08935 (O1Q98_08940) 1975886..1977253 - 1368 WP_125258178.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11651.49 Da        Isoelectric Point: 4.4056

>T266437 WP_125258181.1 NZ_CP114280:1972346-1972651 [Dickeya lacustris]
MQFIVYEYKRASHYTMLVDVQSDIVETPKRRMVIPLIESHRLSEKVNKTLFPLISIDGEDYRLMTTELSSVPVEVIGEVI
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8201.16 Da        Isoelectric Point: 7.2038

>AT266437 WP_012773205.1 NZ_CP114280:1972125-1972343 [Dickeya lacustris]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB E0SK21

References