Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1722896..1723563 Replicon chromosome
Accession NZ_CP114280
Organism Dickeya lacustris strain LMG30899

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag O1Q98_RS07780 Protein ID WP_125258372.1
Coordinates 1723234..1723563 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag O1Q98_RS07775 Protein ID WP_125258373.1
Coordinates 1722896..1723213 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q98_RS07730 (O1Q98_07725) 1718029..1718862 + 834 WP_125258382.1 DUF932 domain-containing protein -
O1Q98_RS07735 (O1Q98_07730) 1719071..1719781 + 711 WP_125258381.1 DeoR family transcriptional regulator -
O1Q98_RS07740 (O1Q98_07735) 1719807..1720343 + 537 WP_125258380.1 DUF4339 domain-containing protein -
O1Q98_RS07745 (O1Q98_07740) 1720385..1720822 + 438 WP_125258379.1 hypothetical protein -
O1Q98_RS07750 (O1Q98_07745) 1720889..1721299 + 411 WP_125258378.1 hypothetical protein -
O1Q98_RS07755 (O1Q98_07750) 1721377..1721613 + 237 WP_125258377.1 DUF905 domain-containing protein -
O1Q98_RS07760 (O1Q98_07755) 1721699..1722157 + 459 WP_125258376.1 antirestriction protein -
O1Q98_RS07765 (O1Q98_07760) 1722166..1722648 + 483 WP_125258375.1 DNA repair protein RadC -
O1Q98_RS07770 (O1Q98_07765) 1722657..1722878 + 222 WP_125258374.1 DUF987 domain-containing protein -
O1Q98_RS07775 (O1Q98_07770) 1722896..1723213 + 318 WP_125258373.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
O1Q98_RS07780 (O1Q98_07775) 1723234..1723563 + 330 WP_125258372.1 TA system toxin CbtA family protein Toxin
O1Q98_RS07785 (O1Q98_07780) 1724265..1725038 - 774 WP_125258394.1 ABC transporter ATP-binding protein -
O1Q98_RS07790 (O1Q98_07785) 1725081..1725974 - 894 WP_240632713.1 ABC transporter ATP-binding protein -
O1Q98_RS07795 (O1Q98_07790) 1725946..1726851 - 906 WP_125258371.1 ABC transporter permease -
O1Q98_RS07800 (O1Q98_07795) 1726848..1727906 - 1059 WP_125258370.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12299.29 Da        Isoelectric Point: 10.1794

>T266435 WP_125258372.1 NZ_CP114280:1723234-1723563 [Dickeya lacustris]
MKNLPATISRAAKPCLSPVSVWQMLLTRLLEQHYGLTLNDTPFSDKTVIQEHINAGVSLSDAVNFLVEKYGLVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 330 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11765.32 Da        Isoelectric Point: 6.7376

>AT266435 WP_125258373.1 NZ_CP114280:1722896-1723213 [Dickeya lacustris]
MSNTTWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVAFPHFISQMDSMLTSGEMNPHHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References