266433

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3022268..3022932 Replicon chromosome
Accession NZ_CP114278
Organism Brevundimonas vesicularis strain Br4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O2K97_RS15050 Protein ID WP_269219892.1
Coordinates 3022498..3022932 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A0S9NKB5
Locus tag O2K97_RS15045 Protein ID WP_017506756.1
Coordinates 3022268..3022501 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2K97_RS15025 3017904..3018749 - 846 WP_269219889.1 tol-pal system protein -
O2K97_RS15030 3018791..3019930 - 1140 WP_269219890.1 DUF3667 domain-containing protein -
O2K97_RS15035 3020058..3020621 - 564 WP_039246161.1 peptidoglycan-associated lipoprotein Pal -
O2K97_RS15040 3020762..3022126 - 1365 WP_269219891.1 Tol-Pal system beta propeller repeat protein TolB -
O2K97_RS15045 3022268..3022501 + 234 WP_017506756.1 hypothetical protein Antitoxin
O2K97_RS15050 3022498..3022932 + 435 WP_269219892.1 VapC toxin family PIN domain ribonuclease Toxin
O2K97_RS15055 3022936..3023814 - 879 WP_269219893.1 cell envelope integrity protein TolA -
O2K97_RS15060 3023820..3024272 - 453 WP_205681722.1 protein TolR -
O2K97_RS15065 3024276..3025028 - 753 WP_269219894.1 protein TolQ -
O2K97_RS15070 3025167..3025601 - 435 WP_269219895.1 hypothetical protein -
O2K97_RS15075 3025628..3026086 - 459 WP_269221149.1 tol-pal system-associated acyl-CoA thioesterase -
O2K97_RS15080 3026092..3026955 - 864 WP_269219896.1 hypothetical protein -
O2K97_RS15085 3026952..3027320 - 369 WP_017506434.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15323.57 Da        Isoelectric Point: 6.6004

>T266433 WP_269219892.1 NZ_CP114278:3022498-3022932 [Brevundimonas vesicularis]
MIALLDVSVLIALIDPAHTEHLTAHAWFANEHQAGWATCPLTENGALRILSNPKYPNSPGAPAQVLPALHSLLSQPGHAF
WPDDISLLGDRLIAQDRLLTSGQLTDTYLLALAVSNGGRLATFDRRLAPDAVKGGKAALHLITA

Download         Length: 435 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8451.61 Da        Isoelectric Point: 8.9990

>AT266433 WP_017506756.1 NZ_CP114278:3022268-3022501 [Brevundimonas vesicularis]
MRTTLAIDDDVLNAARAIAVQTRTSVGEVISDLARRSITQAKPDTSPEFRNGIRLLPHRKGAVVTTEQINALRDELP

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0S9NKB5

References