266431

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-RelB
Location 2910205..2910719 Replicon chromosome
Accession NZ_CP114278
Organism Brevundimonas vesicularis strain Br4

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag O2K97_RS14430 Protein ID WP_269219799.1
Coordinates 2910459..2910719 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6G6RK27
Locus tag O2K97_RS14425 Protein ID WP_039244788.1
Coordinates 2910205..2910462 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2K97_RS14400 2905519..2905935 + 417 WP_269219796.1 DoxX family protein -
O2K97_RS14405 2906112..2906594 + 483 WP_017505872.1 MerR family DNA-binding transcriptional regulator -
O2K97_RS14410 2906598..2908382 + 1785 WP_045809789.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
O2K97_RS14415 2908479..2909642 + 1164 WP_269219797.1 acyl-CoA dehydrogenase family protein -
O2K97_RS14420 2909752..2910084 + 333 WP_269219798.1 GIY-YIG nuclease family protein -
O2K97_RS14425 2910205..2910462 + 258 WP_039244788.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
O2K97_RS14430 2910459..2910719 + 261 WP_269219799.1 Txe/YoeB family addiction module toxin Toxin
O2K97_RS14435 2910716..2911435 + 720 WP_269219800.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
O2K97_RS14440 2911571..2912932 + 1362 WP_269219801.1 glutamate--cysteine ligase -
O2K97_RS14445 2912929..2913666 - 738 WP_269219802.1 hypothetical protein -
O2K97_RS14450 2913778..2915349 + 1572 WP_269219803.1 ATP-binding protein -
O2K97_RS14455 2915404..2915661 + 258 WP_269219804.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10605.08 Da        Isoelectric Point: 9.0388

>T266431 WP_269219799.1 NZ_CP114278:2910459-2910719 [Brevundimonas vesicularis]
MKLTFQTYGWEDYLHWQDHDRKMLRKLNRLIMECQRTPFSGTGKPEPLKGDFSGWWSRRIDQEHRLVYRVTDDALLIAQC
RYHYDR

Download         Length: 261 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9348.50 Da        Isoelectric Point: 4.3566

>AT266431 WP_039244788.1 NZ_CP114278:2910205-2910462 [Brevundimonas vesicularis]
MNAMSVTELRKNLAAAIDRVTADHDYTIITREGGKPAAVLMSLEDFASWQETEYLLRSPANAARLREAISELDAGGGQVR
ELIEE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6G6RK27

References