266429

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 4801..5386 Replicon plasmid pTR3_4
Accession NZ_CP114268
Organism Acinetobacter sp. TR3

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag O1449_RS16005 Protein ID WP_269239835.1
Coordinates 4801..5088 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag O1449_RS16010 Protein ID WP_269239837.1
Coordinates 5075..5386 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1449_RS15975 (O1449_15990) 1..207 - 207 WP_269239826.1 hypothetical protein -
O1449_RS15980 (O1449_15995) 264..806 - 543 WP_269239828.1 plasmid replication DNA-binding protein -
O1449_RS15985 (O1449_16000) 870..1793 - 924 WP_269239830.1 replication initiation protein RepM -
O1449_RS15990 (O1449_16005) 2480..2695 - 216 WP_269239832.1 hypothetical protein -
O1449_RS15995 (O1449_16010) 3665..4027 + 363 WP_180177477.1 hypothetical protein -
O1449_RS16000 (O1449_16015) 4104..4520 + 417 WP_180177476.1 hypothetical protein -
O1449_RS16005 (O1449_16020) 4801..5088 + 288 WP_269239835.1 BrnT family toxin Toxin
O1449_RS16010 (O1449_16025) 5075..5386 + 312 WP_269239837.1 BrnA antitoxin family protein Antitoxin
O1449_RS16015 (O1449_16030) 5460..5753 + 294 WP_269239839.1 hypothetical protein -
O1449_RS16020 (O1449_16035) 5818..6795 - 978 WP_269239841.1 hypothetical protein -
O1449_RS16025 (O1449_16040) 6797..7771 - 975 WP_269239843.1 DGQHR domain-containing protein -
O1449_RS16030 (O1449_16045) 7774..8646 - 873 WP_269239844.1 NotI family restriction endonuclease -
O1449_RS16035 (O1449_16050) 8639..9694 - 1056 WP_269239848.1 site-specific DNA-methyltransferase -
O1449_RS16040 (O1449_16055) 9844..10120 + 277 WP_269239846.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..10120 10120


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11180.61 Da        Isoelectric Point: 4.7784

>T266429 WP_269239835.1 NZ_CP114268:4801-5088 [Acinetobacter sp. TR3]
MELYFEWDEAKNQKNQKKHDVSFETASLIFEDPLRISIQDRHTGGEERWQTIGMVKGVLMLLVAHTIFDEDDCEIIRIIS
AREVTKAERDKYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12056.69 Da        Isoelectric Point: 9.4865

>AT266429 WP_269239837.1 NZ_CP114268:5075-5386 [Acinetobacter sp. TR3]
MSMVRYTRKELNENFSDKQDAEIKRLLAKGTVSDDQLDLSDIPEITDWSNAIRHGQFYRPVKQQTSIRLDADVLAWFKAQ
GKGYQTRMNNILREAMLKDLKNH

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References