Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 2147592..2148358 Replicon chromosome
Accession NZ_CP114264
Organism Acinetobacter sp. TR3

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag O1449_RS10190 Protein ID WP_269229953.1
Coordinates 2147861..2148358 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O1449_RS10185 Protein ID WP_269238237.1
Coordinates 2147592..2147864 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1449_RS10175 (O1449_10190) 2145606..2145827 - 222 WP_269238235.1 hypothetical protein -
O1449_RS10180 (O1449_10195) 2146190..2147530 + 1341 WP_269238236.1 deoxyguanosinetriphosphate triphosphohydrolase -
O1449_RS10185 (O1449_10200) 2147592..2147864 + 273 WP_269238237.1 DUF1778 domain-containing protein Antitoxin
O1449_RS10190 (O1449_10205) 2147861..2148358 + 498 WP_269229953.1 GNAT family N-acetyltransferase Toxin
O1449_RS10195 (O1449_10210) 2148393..2148995 + 603 WP_269238238.1 Holliday junction branch migration protein RuvA -
O1449_RS10200 (O1449_10215) 2149014..2150009 + 996 WP_269229951.1 Holliday junction branch migration DNA helicase RuvB -
O1449_RS10205 (O1449_10220) 2150183..2150590 + 408 WP_004661168.1 tol-pal system-associated acyl-CoA thioesterase -
O1449_RS10210 (O1449_10225) 2150617..2151315 + 699 WP_269238239.1 protein TolQ -
O1449_RS10215 (O1449_10230) 2151315..2151767 + 453 WP_269229949.1 protein TolR -
O1449_RS10220 (O1449_10235) 2151771..2153162 + 1392 WP_269238240.1 cell envelope integrity protein TolA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(81-147)

Antitoxin

Vibrio phage ICP1, Orf50

(5-89)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18721.61 Da        Isoelectric Point: 9.2196

>T266428 WP_269229953.1 NZ_CP114264:2147861-2148358 [Acinetobacter sp. TR3]
MNIILLDKQQHDRQRFDCKNQVLNQYLNQIASQEAKKDNARTYVLIDPVNPAWIMGFYTLTMTSLDLSSLPQSLQKKHAS
VHSAGLIARLAVDHRYQKQGLGAILLLDALHRLYQASAIVAFPLVLVDAKDGIAEFYQQYGFQALSQYPNKLFMTMKDIA
HNIST

Download         Length: 498 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9984.51 Da        Isoelectric Point: 7.4011

>AT266428 WP_269238237.1 NZ_CP114264:2147592-2147864 [Acinetobacter sp. TR3]
MSAYHPRITARVDEQTQALLLQAANLLGMPSLNAFVLSAAIEKAKQVLIQEKSLQLNEKDALALITALDQPIQVHSKLKQ
AAQHYHQTQE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References