Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1079655..1080421 Replicon chromosome
Accession NZ_CP114256
Organism Acinetobacter sp. TR11

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag O1450_RS05205 Protein ID WP_269229953.1
Coordinates 1079655..1080152 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O1450_RS05210 Protein ID WP_269229954.1
Coordinates 1080149..1080421 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1450_RS05175 (O1450_05175) 1074848..1076242 - 1395 WP_269229948.1 cell envelope integrity protein TolA -
O1450_RS05180 (O1450_05180) 1076246..1076698 - 453 WP_269229949.1 protein TolR -
O1450_RS05185 (O1450_05185) 1076698..1077396 - 699 WP_269229950.1 protein TolQ -
O1450_RS05190 (O1450_05190) 1077423..1077830 - 408 WP_004661168.1 tol-pal system-associated acyl-CoA thioesterase -
O1450_RS05195 (O1450_05195) 1078004..1078999 - 996 WP_269229951.1 Holliday junction branch migration DNA helicase RuvB -
O1450_RS05200 (O1450_05200) 1079018..1079620 - 603 WP_269229952.1 Holliday junction branch migration protein RuvA -
O1450_RS05205 (O1450_05205) 1079655..1080152 - 498 WP_269229953.1 GNAT family N-acetyltransferase Toxin
O1450_RS05210 (O1450_05210) 1080149..1080421 - 273 WP_269229954.1 DUF1778 domain-containing protein Antitoxin
O1450_RS05215 (O1450_05215) 1080483..1081823 - 1341 WP_269229955.1 deoxyguanosinetriphosphate triphosphohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(81-147)

Antitoxin

Vibrio phage ICP1, Orf50

(7-85)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18721.61 Da        Isoelectric Point: 9.2196

>T266426 WP_269229953.1 NZ_CP114256:c1080152-1079655 [Acinetobacter sp. TR11]
MNIILLDKQQHDRQRFDCKNQVLNQYLNQIASQEAKKDNARTYVLIDPVNPAWIMGFYTLTMTSLDLSSLPQSLQKKHAS
VHSAGLIARLAVDHRYQKQGLGAILLLDALHRLYQASAIVAFPLVLVDAKDGIAEFYQQYGFQALSQYPNKLFMTMKDIA
HNIST

Download         Length: 498 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9984.47 Da        Isoelectric Point: 6.8771

>AT266426 WP_269229954.1 NZ_CP114256:c1080421-1080149 [Acinetobacter sp. TR11]
MSAYHPRITARVDEQTQALLLQAANLLGMPSLNAFVLSAAIEKAKQVLIQEQSLQLNEKDALALITALDQPIQVHSKLKQ
AAQHYHQTQE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References