Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 3263314..3263987 Replicon chromosome
Accession NZ_CP114201
Organism Delftia acidovorans strain BIM B-1761

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O1V13_RS14735 Protein ID WP_269199065.1
Coordinates 3263577..3263987 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O1V13_RS14730 Protein ID WP_269199064.1
Coordinates 3263314..3263580 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1V13_RS14705 (O1V13_14705) 3258409..3259689 - 1281 WP_013802434.1 TRAP transporter large permease subunit -
O1V13_RS14710 (O1V13_14710) 3259702..3260208 - 507 WP_012205588.1 TRAP transporter small permease -
O1V13_RS14715 (O1V13_14715) 3260227..3260814 - 588 WP_269199063.1 gluconokinase -
O1V13_RS14720 (O1V13_14720) 3260971..3262065 + 1095 WP_012205586.1 LacI family DNA-binding transcriptional regulator -
O1V13_RS14725 (O1V13_14725) 3262102..3263073 - 972 WP_012205585.1 chemotaxis protein -
O1V13_RS14730 (O1V13_14730) 3263314..3263580 + 267 WP_269199064.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
O1V13_RS14735 (O1V13_14735) 3263577..3263987 + 411 WP_269199065.1 type II toxin-antitoxin system VapC family toxin Toxin
O1V13_RS14740 (O1V13_14740) 3264021..3266069 - 2049 WP_063326165.1 acetyl-CoA carboxylase biotin carboxylase subunit -
O1V13_RS14745 (O1V13_14745) 3266281..3267813 - 1533 WP_269199066.1 acyl-CoA carboxylase subunit beta -
O1V13_RS14750 (O1V13_14750) 3267870..3268931 - 1062 WP_269199067.1 methylmalonyl Co-A mutase-associated GTPase MeaB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3252432..3263987 11555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15169.50 Da        Isoelectric Point: 7.3849

>T266422 WP_269199065.1 NZ_CP114201:3263577-3263987 [Delftia acidovorans]
MMLYMLDTNAASEAIRGNPLFDARLQALAPGQWCVGAVTCSELRYGIARRPEAVRLARIVEAFLHITAILPWDARAANQH
GQLRAYLRAQGSPIGDFDEMIAAHALALDAILVTDNVRHFERIPGLRIENWLRQGH

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10127.28 Da        Isoelectric Point: 4.6388

>AT266422 WP_269199064.1 NZ_CP114201:3263314-3263580 [Delftia acidovorans]
MPPVTAQLFATDGVQAVKLPAEFRFEDRAEVYIRRDENTGDVILSTIPRADWSEFMRLRHQLGHAAESALPVRQQSSEQR
DPFQGWEE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References