Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 5555129..5555703 Replicon chromosome
Accession NZ_CP114200
Organism Streptomyces sp. 71268

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag OYE22_RS21925 Protein ID WP_187062828.1
Coordinates 5555326..5555703 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag OYE22_RS21920 Protein ID WP_277321996.1
Coordinates 5555129..5555326 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OYE22_RS21900 (OYE22_21930) 5550324..5551229 + 906 WP_277321993.1 LysR family transcriptional regulator -
OYE22_RS21905 (OYE22_21935) 5551369..5551941 + 573 WP_277321994.1 cysteine dioxygenase family protein -
OYE22_RS21910 (OYE22_21940) 5552127..5553143 + 1017 WP_277324257.1 putative sulfate exporter family transporter -
OYE22_RS21915 (OYE22_21945) 5553432..5555096 + 1665 WP_277321995.1 MFS transporter -
OYE22_RS21920 (OYE22_21950) 5555129..5555326 + 198 WP_277321996.1 Arc family DNA-binding protein Antitoxin
OYE22_RS21925 (OYE22_21955) 5555326..5555703 + 378 WP_187062828.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
OYE22_RS21930 (OYE22_21960) 5555847..5557631 + 1785 WP_176161877.1 DEAD/DEAH box helicase -
OYE22_RS21935 (OYE22_21965) 5558054..5558692 + 639 WP_176161876.1 helix-turn-helix domain-containing protein -
OYE22_RS21940 (OYE22_21970) 5558910..5559689 + 780 WP_277321997.1 S16 family serine protease -
OYE22_RS21945 (OYE22_21975) 5560023..5560643 - 621 Protein_4320 winged helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(23-117)

Antitoxin

Arc-like DNA binding domain

(4-45)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13850.80 Da        Isoelectric Point: 4.6873

>T266419 WP_187062828.1 NZ_CP114200:5555326-5555703 [Streptomyces sp. 71268]
MKFLDLPQLLGLAQRLGESEVRDYGLLESALARPQASVFGQDAYPDVWQKAAALMESLARNHAMVDGNKRLAWYATWVFL
HVNGHPLVEGFDVDEAERFVLNVAQGELDVPKIAELLPRFAASSA

Download         Length: 378 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7324.21 Da        Isoelectric Point: 5.0631

>AT266419 WP_277321996.1 NZ_CP114200:5555129-5555326 [Streptomyces sp. 71268]
MAALNLRFTEEELDALRERAEAEGRSMQAFAHDAVMAAINEHSRLYNEAADHVLKVSAELNRRLA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References