Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 35033..35915 Replicon plasmid pMET1
Accession NZ_CP114191
Organism Aminobacter sp. NyZ550

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N7E70_RS27505 Protein ID WP_263008187.1
Coordinates 35033..35551 (-) Length 173 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A7W3KUD3
Locus tag N7E70_RS27510 Protein ID WP_067967357.1
Coordinates 35544..35915 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E70_RS27490 (N7E70_027485) 31315..31686 - 372 WP_067968412.1 6-carboxytetrahydropterin synthase -
N7E70_RS27495 (N7E70_027490) 31905..32435 + 531 WP_263008185.1 molybdopterin-dependent oxidoreductase -
N7E70_RS27500 (N7E70_027495) 32446..34863 + 2418 WP_263008186.1 EAL domain-containing protein -
N7E70_RS27505 (N7E70_027500) 35033..35551 - 519 WP_263008187.1 RES domain-containing protein Toxin
N7E70_RS27510 (N7E70_027505) 35544..35915 - 372 WP_067967357.1 DUF2384 domain-containing protein Antitoxin
N7E70_RS27515 (N7E70_027510) 36104..36781 - 678 WP_263008188.1 SMC-Scp complex subunit ScpB -
N7E70_RS27520 (N7E70_027515) 36784..37689 - 906 WP_246790261.1 DUF1403 family protein -
N7E70_RS27525 (N7E70_027520) 37920..39752 - 1833 WP_263008189.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..577816 577816


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-165)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(22-63)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19131.75 Da        Isoelectric Point: 6.0852

>T266415 WP_263008187.1 NZ_CP114191:c35551-35033 [Aminobacter sp. NyZ550]
MPEAALRQQRTLWRAFVPRWAHMPLSGEGAARFGGRWNPVGSPTLYAACELSTAWAEYNQGFVQHPALIAQLELSDARLA
DLTVAAILDELGIDAGIHRCEWRSDLDDGRVPETHLLRQRLLTEGFDGVVYPSFMSPGGSCVALWRWNGPGQPSLKIIDP
DQRLPKTQASWL

Download         Length: 519 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13028.98 Da        Isoelectric Point: 10.2736

>AT266415 WP_067967357.1 NZ_CP114191:c35915-35544 [Aminobacter sp. NyZ550]
MAAQSLGMSAAHFGEARSQFLSARRVSELLGVTQADLARLVGVARNTLTARSGARKVDQALSPVVRILAMAAEMAGDESR
AAIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAVRSGVYA

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W3KUD3

References