Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 4274795..4275375 Replicon chromosome
Accession NZ_CP114190
Organism Aminobacter sp. NyZ550

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N7E70_RS21170 Protein ID WP_182573711.1
Coordinates 4274795..4275085 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N7E70_RS21175 Protein ID WP_182573637.1
Coordinates 4275082..4275375 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E70_RS21145 (N7E70_021150) 4270309..4270641 - 333 WP_067966794.1 hypothetical protein -
N7E70_RS21150 (N7E70_021155) 4270695..4272365 - 1671 WP_263007521.1 portal protein -
N7E70_RS21155 (N7E70_021160) 4272365..4272577 - 213 WP_067963548.1 hypothetical protein -
N7E70_RS21160 (N7E70_021165) 4272574..4274148 - 1575 WP_263007522.1 terminase family protein -
N7E70_RS21165 (N7E70_021170) 4274135..4274635 - 501 WP_263007523.1 DNA-packaging protein -
N7E70_RS21170 (N7E70_021175) 4274795..4275085 + 291 WP_182573711.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E70_RS21175 (N7E70_021180) 4275082..4275375 + 294 WP_182573637.1 putative addiction module antidote protein Antitoxin
N7E70_RS21180 (N7E70_021185) 4275516..4275740 - 225 WP_182573636.1 hypothetical protein -
N7E70_RS21185 (N7E70_021190) 4276580..4276921 + 342 WP_263007524.1 hypothetical protein -
N7E70_RS21190 (N7E70_021195) 4277174..4277320 - 147 WP_263007525.1 hypothetical protein -
N7E70_RS21195 (N7E70_021200) 4277496..4277606 + 111 Protein_4185 MarR family transcriptional regulator -
N7E70_RS21200 (N7E70_021205) 4277658..4278437 - 780 WP_263007526.1 SDR family oxidoreductase -
N7E70_RS21205 (N7E70_021210) 4278434..4278757 - 324 WP_263007527.1 nuclear transport factor 2 family protein -
N7E70_RS21210 (N7E70_021215) 4278859..4279773 + 915 WP_263007528.1 LysR family transcriptional regulator -
N7E70_RS21215 (N7E70_021220) 4279959..4280354 - 396 WP_263007529.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - htpB 4241455..4294175 52720


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10677.37 Da        Isoelectric Point: 10.0988

>T266413 WP_182573711.1 NZ_CP114190:4274795-4275085 [Aminobacter sp. NyZ550]
VIEIRRTAEFTGWLTDLKDLKARSRILTRIDRLELGNSGDAKYFDGIGELRVDTGPGYRVYFVKRGTTVVILLCGGDKST
QASDIKKAIAMAKEVK

Download         Length: 291 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10623.08 Da        Isoelectric Point: 4.8723

>AT266413 WP_182573637.1 NZ_CP114190:4275082-4275375 [Aminobacter sp. NyZ550]
MTIKTTKWDAAEFLNSKEEILAYLEAAFEDGDPSGIKLALNNVARARGISDLARETKISREGIYKALSEDGDPKLSTLLS
IVKAFGLNLSVRDLEHA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References