266406

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 583253..583903 Replicon chromosome
Accession NZ_CP114176
Organism Lentibacillus sp. ZS110521

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag O2S85_RS03090 Protein ID WP_269411288.1
Coordinates 583544..583903 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag O2S85_RS03085 Protein ID WP_269411287.1
Coordinates 583253..583540 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2S85_RS03065 578453..578827 + 375 WP_269411284.1 holo-ACP synthase -
O2S85_RS03070 579085..580593 + 1509 WP_269411285.1 NAD(P)H-hydrate dehydratase -
O2S85_RS03075 580681..581742 + 1062 WP_269411286.1 outer membrane lipoprotein carrier protein LolA -
O2S85_RS03080 581913..583043 + 1131 WP_269412454.1 alanine racemase -
O2S85_RS03085 583253..583540 + 288 WP_269411287.1 antitoxin Antitoxin
O2S85_RS03090 583544..583903 + 360 WP_269411288.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
O2S85_RS03095 584063..584932 + 870 WP_269411289.1 RsbT co-antagonist protein RsbRA -
O2S85_RS03100 584939..585295 + 357 WP_269411290.1 STAS domain-containing protein -
O2S85_RS03105 585297..585698 + 402 WP_269411291.1 anti-sigma regulatory factor -
O2S85_RS03110 585782..586792 + 1011 WP_269411292.1 PP2C family protein-serine/threonine phosphatase -
O2S85_RS03115 586877..587209 + 333 WP_269411293.1 STAS domain-containing protein -
O2S85_RS03120 587209..587685 + 477 WP_269412455.1 anti-sigma B factor RsbW -
O2S85_RS03125 587657..588448 + 792 WP_269411294.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13378.61 Da        Isoelectric Point: 9.4870

>T266406 WP_269411288.1 NZ_CP114176:583544-583903 [Lentibacillus sp. ZS110521]
MIVQRGEVYFADLSPVVGSEQGGIRPVLILQNDIGNRFSPTVIIAAITAQIQKAKLPTHVEINAKRYGFDRNSVILLEQI
RTLDKQRLTDKITKLDKEMMEKINHALEISLGLKDMYGS

Download         Length: 360 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10946.32 Da        Isoelectric Point: 4.3097

>AT266406 WP_269411287.1 NZ_CP114176:583253-583540 [Lentibacillus sp. ZS110521]
MSESLQEVLVRIPKNLLNEVDGLMKYENSDLSDFICEATRNYLESKKEEHIQQFRDSMIKGYTEMARINLTIASEAFQAE
EEAEKNTVERSVIGV

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References