Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3668046..3668190 Replicon chromosome
Accession NZ_CP114168
Organism Klebsiella variicola strain 2022CK-00565

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3668082..3668184 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3668046..3668190 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIX89_RS17580 (OIX89_17580) 3663176..3665236 + 2061 WP_071582979.1 oligopeptidase B -
OIX89_RS17585 (OIX89_17585) 3665240..3665899 - 660 WP_008804267.1 exodeoxyribonuclease X -
OIX89_RS17590 (OIX89_17590) 3665978..3666208 - 231 WP_012541260.1 DNA polymerase III subunit theta -
OIX89_RS17595 (OIX89_17595) 3666322..3666696 + 375 WP_016161388.1 CopC domain-containing protein YobA -
OIX89_RS17600 (OIX89_17600) 3666700..3667569 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
OIX89_RS17605 (OIX89_17605) 3667586..3667924 + 339 WP_008804271.1 YebY family protein -
- 3668046..3668190 - 145 - - Antitoxin
- 3668082..3668184 + 103 - - Toxin
OIX89_RS17610 (OIX89_17610) 3668569..3668712 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
OIX89_RS17615 (OIX89_17615) 3668816..3669784 - 969 WP_162493241.1 VirK/YbjX family protein -
OIX89_RS17620 (OIX89_17620) 3669941..3670594 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
OIX89_RS17625 (OIX89_17625) 3670591..3670782 - 192 WP_002911395.1 YebW family protein -
OIX89_RS17630 (OIX89_17630) 3670880..3671119 - 240 WP_002911393.1 YebV family protein -
OIX89_RS17635 (OIX89_17635) 3671235..3672668 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T266398 NZ_CP114168:3668082-3668184 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT266398 NZ_CP114168:c3668190-3668046 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References