Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 4674515..4675334 Replicon chromosome
Accession NZ_CP114156
Organism Klebsiella michiganensis strain 2022CK-00497

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag OEE44_RS22150 Protein ID WP_004110819.1
Coordinates 4675077..4675334 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag OEE44_RS22145 Protein ID WP_182094342.1
Coordinates 4674515..4675066 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEE44_RS22125 (OEE44_22125) 4669885..4671282 + 1398 WP_032718963.1 MFS transporter -
OEE44_RS22130 (OEE44_22130) 4671404..4672744 + 1341 WP_014228059.1 carbohydrate porin -
OEE44_RS22135 (OEE44_22135) 4672869..4673615 - 747 WP_228304563.1 class I SAM-dependent methyltransferase -
OEE44_RS22140 (OEE44_22140) 4674039..4674401 - 363 Protein_4357 class I SAM-dependent methyltransferase -
OEE44_RS22145 (OEE44_22145) 4674515..4675066 - 552 WP_182094342.1 N-acetyltransferase Antitoxin
OEE44_RS22150 (OEE44_22150) 4675077..4675334 - 258 WP_004110819.1 YjhX family toxin Toxin
OEE44_RS22155 (OEE44_22155) 4676010..4677194 + 1185 WP_014228054.1 mannonate dehydratase -
OEE44_RS22160 (OEE44_22160) 4677268..4678743 + 1476 WP_014228053.1 fructuronate reductase -
OEE44_RS22165 (OEE44_22165) 4678882..4679658 + 777 WP_004847986.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T266350 WP_004110819.1 NZ_CP114156:c4675334-4675077 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19931.79 Da        Isoelectric Point: 6.3260

>AT266350 WP_182094342.1 NZ_CP114156:c4675066-4674515 [Klebsiella michiganensis]
MTNHSFTIHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGELIRHGIEQLKAMGSQMVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPAAHKACWMLQPISS
QPLGRTGQIQCALALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References