Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2151144..2151312 Replicon chromosome
Accession NZ_CP114149
Organism Klebsiella michiganensis strain 2022CK-00496

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2151202..2151305 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2151144..2151312 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEE45_RS10255 (OEE45_10260) 2146271..2148331 + 2061 WP_033836507.1 oligopeptidase B -
OEE45_RS10260 (OEE45_10265) 2148338..2148997 - 660 WP_014229839.1 exodeoxyribonuclease X -
OEE45_RS10265 (OEE45_10270) 2149076..2149306 - 231 WP_004103351.1 DNA polymerase III subunit theta -
OEE45_RS10270 (OEE45_10275) 2149442..2149816 + 375 WP_014229838.1 CopC domain-containing protein YobA -
OEE45_RS10275 (OEE45_10280) 2149821..2150690 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
OEE45_RS10280 (OEE45_10285) 2150707..2151045 + 339 WP_004103344.1 YebY family protein -
- 2151144..2151312 - 169 - - Antitoxin
- 2151202..2151305 + 104 - - Toxin
OEE45_RS10285 (OEE45_10290) 2151430..2152389 - 960 WP_042945476.1 spore coat protein U domain-containing protein -
OEE45_RS10290 (OEE45_10295) 2152404..2154734 - 2331 WP_064405637.1 fimbria/pilus outer membrane usher protein -
OEE45_RS10295 (OEE45_10300) 2154737..2155501 - 765 WP_049082702.1 fimbria/pilus periplasmic chaperone -
OEE45_RS10300 (OEE45_10305) 2155520..2156038 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T266330 NZ_CP114149:2151202-2151305 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT266330 NZ_CP114149:c2151312-2151144 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References