Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4054301..4054968 Replicon chromosome
Accession NZ_CP114134
Organism Xanthomonas fragariae strain YLX21

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OZ429_RS19175 Protein ID WP_269123884.1
Coordinates 4054552..4054968 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OZ429_RS19170 Protein ID WP_269123882.1
Coordinates 4054301..4054555 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ429_RS19145 (OZ429_19145) 4050121..4050255 + 135 WP_269123877.1 hypothetical protein -
OZ429_RS19150 (OZ429_19150) 4050312..4051445 - 1134 WP_269123878.1 hypothetical protein -
OZ429_RS19160 (OZ429_19160) 4052857..4053063 + 207 WP_269123880.1 hypothetical protein -
OZ429_RS19165 (OZ429_19165) 4053050..4054162 + 1113 WP_269127066.1 type II toxin-antitoxin system RelE/ParE family toxin -
OZ429_RS19170 (OZ429_19170) 4054301..4054555 + 255 WP_269123882.1 Arc family DNA-binding protein Antitoxin
OZ429_RS19175 (OZ429_19175) 4054552..4054968 + 417 WP_269123884.1 PIN domain-containing protein Toxin
OZ429_RS19180 (OZ429_19180) 4055028..4055261 + 234 WP_269123886.1 hypothetical protein -
OZ429_RS19185 (OZ429_19185) 4055266..4056018 + 753 WP_269123888.1 DUF3800 domain-containing protein -
OZ429_RS19190 (OZ429_19190) 4056094..4057371 - 1278 WP_269123891.1 HipA domain-containing protein -
OZ429_RS19195 (OZ429_19195) 4057368..4057568 - 201 WP_269123893.1 helix-turn-helix domain-containing protein -
OZ429_RS19200 (OZ429_19200) 4057803..4057967 - 165 WP_269123895.1 hypothetical protein -
OZ429_RS19205 (OZ429_19205) 4058046..4059653 + 1608 WP_269123897.1 alpha/beta hydrolase-fold protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 4049655..4050041 386


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-46)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14937.29 Da        Isoelectric Point: 5.6142

>T266325 WP_269123884.1 NZ_CP114134:4054552-4054968 [Xanthomonas fragariae]
VILLDTNVISELWRPQPNPKVVAWIDAQAVETLFLSVVTVAELRFGIAVMPEGRKRYTLHARLESDVLPLFDGRLLAFDL
DASHAFATLASKARTAGLTLGRADAYIAATAAAHALAVATRDTAPFEAMALDVINPWI

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8989.42 Da        Isoelectric Point: 11.0116

>AT266325 WP_269123882.1 NZ_CP114134:4054301-4054555 [Xanthomonas fragariae]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILESAAKPAGRVKLGSLLVDIGRDAGLTAKEANAFDTMRDKAAIKP
LGLK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References