Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3043619..3044397 Replicon chromosome
Accession NZ_CP114134
Organism Xanthomonas fragariae strain YLX21

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag OZ429_RS14305 Protein ID WP_269122574.1
Coordinates 3043906..3044397 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID G0CD67
Locus tag OZ429_RS14300 Protein ID WP_014508712.1
Coordinates 3043619..3043909 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ429_RS14290 (OZ429_14290) 3039919..3042498 + 2580 WP_269122571.1 RHS repeat domain-containing protein -
OZ429_RS14295 (OZ429_14295) 3043139..3043543 + 405 WP_269122573.1 SymE family type I addiction module toxin -
OZ429_RS14300 (OZ429_14300) 3043619..3043909 + 291 WP_014508712.1 DUF1778 domain-containing protein Antitoxin
OZ429_RS14305 (OZ429_14305) 3043906..3044397 + 492 WP_269122574.1 GNAT family N-acetyltransferase Toxin
OZ429_RS14310 (OZ429_14310) 3044546..3045880 - 1335 WP_269122576.1 HAMP domain-containing sensor histidine kinase -
OZ429_RS14315 (OZ429_14315) 3046339..3047016 - 678 WP_002804927.1 response regulator transcription factor -
OZ429_RS14320 (OZ429_14320) 3047042..3047485 - 444 Protein_2684 hypothetical protein -
OZ429_RS14325 (OZ429_14325) 3047708..3048613 - 906 WP_208589518.1 30S ribosomal protein S6--L-glutamate ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17549.20 Da        Isoelectric Point: 8.9888

>T266323 WP_269122574.1 NZ_CP114134:3043906-3044397 [Xanthomonas fragariae]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRAFVACADDRVVAYYALASSAVAVDATPGRFRRNMPDQ
IPVVVLGRLAVDQSLHGRGFGRALVQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10648.20 Da        Isoelectric Point: 10.5480

>AT266323 WP_014508712.1 NZ_CP114134:3043619-3043909 [Xanthomonas fragariae]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLIAASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3E1LB51

References