Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1493524..1494203 Replicon chromosome
Accession NZ_CP114134
Organism Xanthomonas fragariae strain YLX21

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OZ429_RS07095 Protein ID WP_269125924.1
Coordinates 1493524..1493886 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OZ429_RS07100 Protein ID WP_208590306.1
Coordinates 1493886..1494203 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ429_RS07075 (OZ429_07075) 1489424..1490229 + 806 WP_269121653.1 IS5 family transposase -
OZ429_RS07080 (OZ429_07080) 1490415..1490693 - 279 Protein_1329 NAD(P)H-dependent oxidoreductase -
OZ429_RS07085 (OZ429_07085) 1490796..1491809 + 1014 WP_269125920.1 LysR family transcriptional regulator -
OZ429_RS07095 (OZ429_07095) 1493524..1493886 + 363 WP_269125924.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZ429_RS07100 (OZ429_07100) 1493886..1494203 + 318 WP_208590306.1 helix-turn-helix transcriptional regulator Antitoxin
OZ429_RS07105 (OZ429_07105) 1494249..1495733 - 1485 WP_269125927.1 site-specific integrase -
OZ429_RS07115 (OZ429_07115) 1496306..1497256 - 951 WP_269125929.1 IS481 family transposase -
OZ429_RS07120 (OZ429_07120) 1497438..1498217 + 780 WP_269125931.1 hypothetical protein -
OZ429_RS07125 (OZ429_07125) 1498374..1498934 + 561 WP_269125933.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1489843..1518941 29098
- inside IScluster/Tn - - 1489843..1500129 10286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-108)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-91)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13491.36 Da        Isoelectric Point: 7.1653

>T266322 WP_269125924.1 NZ_CP114134:1493524-1493886 [Xanthomonas fragariae]
MPEKPLIWVGSSRRDLAELPEDVKDTFGFALSEAQNGRTHVRAKPMAKGSLKGKGIYEVVDDYDGDTFRAVYTVEIEDAI
YALHCFQKKSKNGRETPKSDIDLIESRYQAALLDAKKVKI

Download         Length: 363 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11121.71 Da        Isoelectric Point: 4.8040

>AT266322 WP_208590306.1 NZ_CP114134:1493886-1494203 [Xanthomonas fragariae]
MSIEIEVSSGNIYSDLGYSNAEEMKIKAALAGKISAFIADAHLTQAQAAAHMGISQAKVSEMLRGRFRGISEAKMMECLK
SFGQNVTISVTPAEVPDEAEISVAA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References