Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1493524..1494203 Replicon chromosome
Accession NZ_CP114134
Organism Xanthomonas fragariae strain YLX21

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OZ429_RS07095 Protein ID WP_269125924.1
Coordinates 1493524..1493886 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OZ429_RS07100 Protein ID WP_208590306.1
Coordinates 1493886..1494203 (+) Length 106 a.a.

Genomic Context

OZ429_RS07075OZ429_RS07085OZ429_RS07095OZ429_RS07100OZ429_RS07120OZ429_RS07125OZ429_RS07080OZ429_RS07105OZ429_RS07115
Location: 1489424..1490229 (806 bp)
Type: Others
Protein ID: WP_269121653.1
Location: 1490796..1491809 (1014 bp)
Type: Others
Protein ID: WP_269125920.1
Location: 1493524..1493886 (363 bp)
Type: Toxin
Protein ID: WP_269125924.1
Location: 1493886..1494203 (318 bp)
Type: Antitoxin
Protein ID: WP_208590306.1
Location: 1497438..1498217 (780 bp)
Type: Others
Protein ID: WP_269125931.1
Location: 1498374..1498934 (561 bp)
Type: Others
Protein ID: WP_269125933.1
Location: 1490415..1490693 (279 bp)
Type: Others
Protein ID: Protein_1329
Location: 1494249..1495733 (1485 bp)
Type: Others
Protein ID: WP_269125927.1
Location: 1496306..1497256 (951 bp)
Type: Others
Protein ID: WP_269125929.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OZ429_RS07075 (OZ429_07075)1489424..1490229+806WP_269121653.1IS5 family transposase-
OZ429_RS07080 (OZ429_07080)1490415..1490693-279Protein_1329NAD(P)H-dependent oxidoreductase-
OZ429_RS07085 (OZ429_07085)1490796..1491809+1014WP_269125920.1LysR family transcriptional regulator-
OZ429_RS07095 (OZ429_07095)1493524..1493886+363WP_269125924.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OZ429_RS07100 (OZ429_07100)1493886..1494203+318WP_208590306.1helix-turn-helix transcriptional regulatorAntitoxin
OZ429_RS07105 (OZ429_07105)1494249..1495733-1485WP_269125927.1site-specific integrase-
OZ429_RS07115 (OZ429_07115)1496306..1497256-951WP_269125929.1IS481 family transposase-
OZ429_RS07120 (OZ429_07120)1497438..1498217+780WP_269125931.1hypothetical protein-
OZ429_RS07125 (OZ429_07125)1498374..1498934+561WP_269125933.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1489843..151894129098
-insideIScluster/Tn--1489843..150012910286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-108)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-91)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13491.36 Da        Isoelectric Point: 7.1653

>T266322 WP_269125924.1 NZ_CP114134:1493524-1493886 [Xanthomonas fragariae]
MPEKPLIWVGSSRRDLAELPEDVKDTFGFALSEAQNGRTHVRAKPMAKGSLKGKGIYEVVDDYDGDTFRAVYTVEIEDAI
YALHCFQKKSKNGRETPKSDIDLIESRYQAALLDAKKVKI

Download         Length: 363 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11121.71 Da        Isoelectric Point: 4.8040

>AT266322 WP_208590306.1 NZ_CP114134:1493886-1494203 [Xanthomonas fragariae]
MSIEIEVSSGNIYSDLGYSNAEEMKIKAALAGKISAFIADAHLTQAQAAAHMGISQAKVSEMLRGRFRGISEAKMMECLK
SFGQNVTISVTPAEVPDEAEISVAA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References