Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 354063..354817 Replicon chromosome
Accession NZ_CP114128
Organism Escherichia coli strain PE164

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag LZG51_RS01585 Protein ID WP_001301452.1
Coordinates 354063..354548 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag LZG51_RS01590 Protein ID WP_000801914.1
Coordinates 354539..354817 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZG51_RS01565 (349229) 349229..349987 + 759 WP_000815099.1 DeoR/GlpR family transcriptional regulator -
LZG51_RS01570 (349969) 349969..351567 - 1599 WP_153645359.1 DNA-binding transcriptional regulator RtcR -
LZG51_RS01575 (351754) 351754..352981 + 1228 Protein_312 RNA-splicing ligase RtcB -
LZG51_RS01580 (352985) 352985..354013 + 1029 WP_053883632.1 RNA 3'-terminal phosphate cyclase -
LZG51_RS01585 (354063) 354063..354548 - 486 WP_001301452.1 GNAT family N-acetyltransferase Toxin
LZG51_RS01590 (354539) 354539..354817 - 279 WP_000801914.1 DUF1778 domain-containing protein Antitoxin
LZG51_RS01595 (354884) 354884..357589 - 2706 WP_000906960.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-143)

Antitoxin

Vibrio phage ICP1, Orf50

(2-92)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17650.57 Da        Isoelectric Point: 9.4066

>T266267 WP_001301452.1 NZ_CP114128:c354548-354063 [Escherichia coli]
MGITAPTPLTSEHNLADFCCSDHGMNEWLKKKALKNHSSGLSRVYVICIANTRQVIGYYCLSTGSIQRNLAPGAMRRNAP
ESLPVVVLGRLAIDQAWAGKGLGVALLKDAVYRTMSIAQQVGVRALIVHALDDSVRNFYLKYAFVPSPFQSLTLLYPITL
E

Download         Length: 486 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10406.91 Da        Isoelectric Point: 4.6336

>AT266267 WP_000801914.1 NZ_CP114128:c354817-354539 [Escherichia coli]
MKPESKEAPINIRAKASQRDLIDMAANLVAKSRTDFMLDAACREAQDILLDQRLFIVDDEQYDAFLAALDAPITAERQAK
INALMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References