Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6637790..6638306 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZ428_RS31430 Protein ID WP_269132241.1
Coordinates 6637790..6638077 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W2E0E6
Locus tag OZ428_RS31435 Protein ID WP_033897026.1
Coordinates 6638067..6638306 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS31410 (OZ428_31410) 6633384..6634331 - 948 WP_269132240.1 FecR family protein -
OZ428_RS31415 (OZ428_31415) 6634328..6634861 - 534 WP_133075476.1 RNA polymerase sigma factor -
OZ428_RS31420 (OZ428_31420) 6635068..6636066 - 999 WP_269134240.1 haloacid dehalogenase-like hydrolase -
OZ428_RS31425 (OZ428_31425) 6636367..6637758 + 1392 WP_177110227.1 L-cystine transporter -
OZ428_RS31430 (OZ428_31430) 6637790..6638077 - 288 WP_269132241.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZ428_RS31435 (OZ428_31435) 6638067..6638306 - 240 WP_033897026.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZ428_RS31440 (OZ428_31440) 6638390..6638902 - 513 WP_269132242.1 dihydrofolate reductase -
OZ428_RS31445 (OZ428_31445) 6638972..6640342 + 1371 WP_269132243.1 DUF2868 domain-containing protein -
OZ428_RS31450 (OZ428_31450) 6640335..6641702 + 1368 WP_269132245.1 DUF3482 domain-containing protein -
OZ428_RS31455 (OZ428_31455) 6641708..6642241 - 534 WP_133075481.1 hypothetical protein -
OZ428_RS31460 (OZ428_31460) 6642333..6642887 - 555 WP_133075482.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11223.02 Da        Isoelectric Point: 9.8418

>T266264 WP_269132241.1 NZ_CP114115:c6638077-6637790 [Pseudomonas sp. GXZC]
MTYELDFDARALKEWHKLGDTVRQQFKKKLAAVLINPRIEASRLYGLPDCYKIKLRSSGYRLVYQVIDQEITVFVVAVDK
REREEVYRKAADRLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8949.32 Da        Isoelectric Point: 4.7962

>AT266264 WP_033897026.1 NZ_CP114115:c6638306-6638067 [Pseudomonas sp. GXZC]
MASINVRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W2E0E6

References