Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5932590..5933095 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZ428_RS28050 Protein ID WP_135309690.1
Coordinates 5932841..5933095 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID W2E3T5
Locus tag OZ428_RS28045 Protein ID WP_033896223.1
Coordinates 5932590..5932844 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS28030 (OZ428_28030) 5928107..5929006 + 900 WP_269131976.1 LysR substrate-binding domain-containing protein -
OZ428_RS28035 (OZ428_28035) 5929090..5930340 + 1251 WP_269131977.1 aspartate aminotransferase family protein -
OZ428_RS28040 (OZ428_28040) 5930337..5932361 - 2025 WP_269131978.1 c-type cytochrome -
OZ428_RS28045 (OZ428_28045) 5932590..5932844 + 255 WP_033896223.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OZ428_RS28050 (OZ428_28050) 5932841..5933095 + 255 WP_135309690.1 Txe/YoeB family addiction module toxin Toxin
OZ428_RS28055 (OZ428_28055) 5933165..5933668 + 504 WP_269131979.1 hypothetical protein -
OZ428_RS28060 (OZ428_28060) 5933739..5934461 + 723 WP_269131980.1 hypothetical protein -
OZ428_RS28065 (OZ428_28065) 5934507..5935709 - 1203 WP_269131981.1 MFS transporter -
OZ428_RS28070 (OZ428_28070) 5935881..5936573 - 693 WP_269131982.1 LuxR family transcriptional regulator -
OZ428_RS28075 (OZ428_28075) 5936716..5937807 - 1092 WP_269131983.1 pyridoxal phosphate-dependent aminotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10035.54 Da        Isoelectric Point: 7.2753

>T266263 WP_135309690.1 NZ_CP114115:5932841-5933095 [Pseudomonas sp. GXZC]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFDGVGKPEPLKHNLSGFWSRRITAEHRLVYGIEDDEVQILMC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9588.99 Da        Isoelectric Point: 7.2037

>AT266263 WP_033896223.1 NZ_CP114115:5932590-5932844 [Pseudomonas sp. GXZC]
METINYTNARAHLAETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRR
LIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W2E3T5

References