Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 5907565..5908607 | Replicon | chromosome |
| Accession | NZ_CP114115 | ||
| Organism | Pseudomonas sp. GXZC | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | OZ428_RS27930 | Protein ID | WP_269131961.1 |
| Coordinates | 5907565..5908140 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | OZ428_RS27935 | Protein ID | WP_269131962.1 |
| Coordinates | 5908137..5908607 (-) | Length | 157 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OZ428_RS27905 (OZ428_27905) | 5904382..5905347 | - | 966 | WP_269131957.1 | FecR domain-containing protein | - |
| OZ428_RS27910 (OZ428_27910) | 5905344..5905880 | - | 537 | WP_269134230.1 | sigma-70 family RNA polymerase sigma factor | - |
| OZ428_RS27915 (OZ428_27915) | 5906059..5906388 | + | 330 | WP_269131958.1 | hypothetical protein | - |
| OZ428_RS27920 (OZ428_27920) | 5906397..5907032 | - | 636 | WP_269131959.1 | LysE family translocator | - |
| OZ428_RS27925 (OZ428_27925) | 5907160..5907531 | + | 372 | WP_269131960.1 | PH domain-containing protein | - |
| OZ428_RS27930 (OZ428_27930) | 5907565..5908140 | - | 576 | WP_269131961.1 | PIN domain-containing protein | Toxin |
| OZ428_RS27935 (OZ428_27935) | 5908137..5908607 | - | 471 | WP_269131962.1 | helix-turn-helix domain-containing protein | Antitoxin |
| OZ428_RS27940 (OZ428_27940) | 5908817..5909389 | - | 573 | WP_269131963.1 | hypothetical protein | - |
| OZ428_RS27945 (OZ428_27945) | 5909459..5910814 | - | 1356 | WP_269131964.1 | sensor histidine kinase | - |
| OZ428_RS27950 (OZ428_27950) | 5910811..5911473 | - | 663 | WP_033896241.1 | response regulator | - |
| OZ428_RS27955 (OZ428_27955) | 5911621..5911887 | + | 267 | WP_033896240.1 | PepSY domain-containing protein | - |
| OZ428_RS27960 (OZ428_27960) | 5911887..5912432 | + | 546 | WP_269131965.1 | cytochrome b/b6 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21692.05 Da Isoelectric Point: 4.8780
>T266262 WP_269131961.1 NZ_CP114115:c5908140-5907565 [Pseudomonas sp. GXZC]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTSQIHEEWKRNVLKNRPDLTAEQVNCTSELMDKAIPDALVTAY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPPHILAAYDIEPMHPDDFISDLWDLDQAAVLGAAQKQRRALRR
PPMEAGNYLEMLMRQGLVQTSKVLGPYEMML
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTSQIHEEWKRNVLKNRPDLTAEQVNCTSELMDKAIPDALVTAY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPPHILAAYDIEPMHPDDFISDLWDLDQAAVLGAAQKQRRALRR
PPMEAGNYLEMLMRQGLVQTSKVLGPYEMML
Download Length: 576 bp
Antitoxin
Download Length: 157 a.a. Molecular weight: 17464.17 Da Isoelectric Point: 6.6510
>AT266262 WP_269131962.1 NZ_CP114115:c5908607-5908137 [Pseudomonas sp. GXZC]
MITNHLPKTILPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELAIGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRTEESQRAMEALAQQAQELGMGYDG
MITNHLPKTILPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELAIGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRTEESQRAMEALAQQAQELGMGYDG
Download Length: 471 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|