Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 5555349..5555989 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag OZ428_RS26190 Protein ID WP_269131788.1
Coordinates 5555349..5555762 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag OZ428_RS26195 Protein ID WP_269131789.1
Coordinates 5555759..5555989 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS26170 (OZ428_26170) 5550444..5551133 - 690 WP_010208305.1 ABC transporter permease -
OZ428_RS26175 (OZ428_26175) 5551225..5552010 - 786 WP_033901307.1 ABC transporter substrate-binding protein -
OZ428_RS26180 (OZ428_26180) 5552572..5554527 - 1956 WP_033902234.1 acetate--CoA ligase -
OZ428_RS26185 (OZ428_26185) 5554939..5555208 + 270 WP_033902233.1 DUF2790 domain-containing protein -
OZ428_RS26190 (OZ428_26190) 5555349..5555762 - 414 WP_269131788.1 type II toxin-antitoxin system VapC family toxin Toxin
OZ428_RS26195 (OZ428_26195) 5555759..5555989 - 231 WP_269131789.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OZ428_RS26200 (OZ428_26200) 5556470..5557720 + 1251 WP_005790649.1 ribonucleotide-diphosphate reductase subunit beta -
OZ428_RS26205 (OZ428_26205) 5557813..5557945 + 133 Protein_5170 HNH endonuclease -
OZ428_RS26210 (OZ428_26210) 5558018..5558659 + 642 WP_038846731.1 HAD-IB family hydrolase -
OZ428_RS26215 (OZ428_26215) 5558783..5559007 - 225 WP_269131790.1 hypothetical protein -
OZ428_RS26220 (OZ428_26220) 5559196..5560155 - 960 WP_269131791.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-128)

Antitoxin

SpoVT-AbrB domain

(7-47)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15180.51 Da        Isoelectric Point: 6.6986

>T266261 WP_269131788.1 NZ_CP114115:c5555762-5555349 [Pseudomonas sp. GXZC]
VTTYMLDTCICSFIMRERPECVLERLAAEVARSNRIVISAITYSEMRYGQIGKKASPKHKTLVDEFLRRLDEVLPWGLAA
VDATVEVKRSLAEAGLIIGQNDTAIAGHAIAAGCTLVTNNVREFSRVPGLSYEDWVH

Download         Length: 414 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8620.68 Da        Isoelectric Point: 4.7571

>AT266261 WP_269131789.1 NZ_CP114115:c5555989-5555759 [Pseudomonas sp. GXZC]
MRTVSIFKNGKNQAIRLPNDMAYEGVGELEITRNGDTITLRPVRPSWGSLSDLPKADEDFLRERQDVIGDEGRFNL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References