Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 789007..789599 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OZ428_RS03655 Protein ID WP_269132730.1
Coordinates 789291..789599 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZ428_RS03650 Protein ID WP_233893633.1
Coordinates 789007..789294 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS03630 (OZ428_03630) 785429..787489 - 2061 WP_269132727.1 TonB-dependent copper receptor -
OZ428_RS03635 (OZ428_03635) 787583..787972 - 390 WP_016976979.1 DUF2946 domain-containing protein -
OZ428_RS03640 (OZ428_03640) 787984..788466 - 483 WP_269132728.1 copper chaperone PCu(A)C -
OZ428_RS03645 (OZ428_03645) 788514..788909 - 396 WP_269132729.1 DUF2946 domain-containing protein -
OZ428_RS03650 (OZ428_03650) 789007..789294 - 288 WP_233893633.1 putative addiction module antidote protein Antitoxin
OZ428_RS03655 (OZ428_03655) 789291..789599 - 309 WP_269132730.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZ428_RS03660 (OZ428_03660) 789949..790668 - 720 WP_269132731.1 cobalt-precorrin-6A reductase -
OZ428_RS03665 (OZ428_03665) 790665..791870 - 1206 WP_269132732.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
OZ428_RS03670 (OZ428_03670) 791909..793255 + 1347 WP_269132733.1 precorrin-3B synthase -
OZ428_RS03675 (OZ428_03675) 793248..793874 + 627 WP_016976987.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(2-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11702.15 Da        Isoelectric Point: 9.5427

>T266251 WP_269132730.1 NZ_CP114115:c789599-789291 [Pseudomonas sp. GXZC]
MIRFKRSDEFQEWLDSSRSRPARGRVLTRLDNATRGNFGDCAPVGNGVSEMRIHYGPGYRVYFTRVDEVVYLLLIGGDKS
TQKRDIQRAKEIADEFGIRSDS

Download         Length: 309 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10360.84 Da        Isoelectric Point: 4.8047

>AT266251 WP_233893633.1 NZ_CP114115:c789294-789007 [Pseudomonas sp. GXZC]
MTQFKDFDIAEHLKTPEDMAEYLEASFEEDSGDGLLIRSALNNIARAQGMTQIARDAGLGRESLYKALSATGNPEFATIM
KVMKALGLKLHATAI

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References