Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4836317..4837031 Replicon chromosome
Accession NZ_CP114062
Organism Rouxiella badensis strain DAR84756

Toxin (Protein)


Gene name cptA Uniprot ID A0A1X0WDA6
Locus tag O1V65_RS22345 Protein ID WP_038328038.1
Coordinates 4836564..4837031 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1X0WD57
Locus tag O1V65_RS22340 Protein ID WP_017492114.1
Coordinates 4836317..4836583 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1V65_RS22325 (O1V65_22320) 4831643..4832290 + 648 WP_269130046.1 hemolysin III family protein -
O1V65_RS22330 (O1V65_22325) 4832506..4834935 + 2430 WP_269130047.1 M60 family metallopeptidase -
O1V65_RS22335 (O1V65_22330) 4835047..4836039 - 993 WP_017491354.1 tRNA-modifying protein YgfZ -
O1V65_RS22340 (O1V65_22335) 4836317..4836583 + 267 WP_017492114.1 FAD assembly factor SdhE Antitoxin
O1V65_RS22345 (O1V65_22340) 4836564..4837031 + 468 WP_038328038.1 protein YgfX Toxin
O1V65_RS22350 (O1V65_22345) 4837053..4837571 - 519 WP_017492112.1 flavodoxin FldB -
O1V65_RS22355 (O1V65_22350) 4837728..4838609 + 882 WP_038328043.1 site-specific tyrosine recombinase XerD -
O1V65_RS22360 (O1V65_22355) 4838636..4839343 + 708 WP_017492110.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
O1V65_RS22365 (O1V65_22360) 4839406..4841139 + 1734 WP_026110554.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-140)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 18280.52 Da        Isoelectric Point: 11.7962

>T266246 WP_038328038.1 NZ_CP114062:4836564-4837031 [Rouxiella badensis]
VALWQCDLRVSWRSQLFSLAVHGILILLILLAPWPPDDWMIWLILLIIVVSQSIRSQRRISARQGEISLLAQDRLLWRKQ
EWKIKQPVWMIDSGILLSLRRERTGHGWRQALRGKKHKLWLASDSMSQEEWRHLRQILLTGKRDAAPANNNHHPL

Download         Length: 468 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10563.10 Da        Isoelectric Point: 4.6436

>AT266246 WP_017492114.1 NZ_CP114062:4836317-4836583 [Rouxiella badensis]
MDINNKPRIHWACRRGMKELDLAILPFFEYEFDTLSDEDKQQFARLLECDDPDLFNWLMNYGEPNDLELKRMVNLIQTRN
KQRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X0WDA6

Antitoxin

Source ID Structure
AlphaFold DB A0A1X0WD57

References