Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 2966563..2967258 Replicon chromosome
Accession NZ_CP114062
Organism Rouxiella badensis strain DAR84756

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag O1V65_RS13755 Protein ID WP_269129793.1
Coordinates 2966563..2966883 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag O1V65_RS13760 Protein ID WP_269129794.1
Coordinates 2966935..2967258 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1V65_RS13730 (O1V65_13725) 2962364..2963209 + 846 WP_017492635.1 DeoR/GlpR family DNA-binding transcription regulator -
O1V65_RS13735 (O1V65_13730) 2963206..2964006 - 801 WP_017492636.1 SDR family oxidoreductase -
O1V65_RS13740 (O1V65_13735) 2964118..2964381 - 264 WP_017492637.1 DUF2798 domain-containing protein -
O1V65_RS13745 (O1V65_13740) 2964510..2965409 + 900 WP_269129791.1 LysR family transcriptional regulator -
O1V65_RS13750 (O1V65_13745) 2965616..2966449 - 834 WP_269129792.1 DUF4942 domain-containing protein -
O1V65_RS13755 (O1V65_13750) 2966563..2966883 - 321 WP_269129793.1 TA system toxin CbtA family protein Toxin
O1V65_RS13760 (O1V65_13755) 2966935..2967258 - 324 WP_269129794.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
O1V65_RS13765 (O1V65_13760) 2967271..2967741 - 471 WP_269129795.1 DNA repair protein RadC -
O1V65_RS13770 (O1V65_13765) 2967807..2968628 - 822 WP_269129796.1 DUF932 domain-containing protein -
O1V65_RS13775 (O1V65_13770) 2968844..2969155 - 312 WP_269129797.1 hypothetical protein -
O1V65_RS13780 (O1V65_13775) 2969168..2969452 - 285 WP_269129798.1 hypothetical protein -
O1V65_RS13785 (O1V65_13780) 2969518..2970024 - 507 WP_269129799.1 hypothetical protein -
O1V65_RS13790 (O1V65_13785) 2970021..2970749 - 729 WP_269129800.1 WYL domain-containing protein -
O1V65_RS13795 (O1V65_13790) 2970969..2971853 - 885 WP_269129801.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12060.77 Da        Isoelectric Point: 6.8779

>T266244 WP_269129793.1 NZ_CP114062:c2966883-2966563 [Rouxiella badensis]
MQISTVPATVPVSSRLSPVQTWQQLLTYLLDHHYGLVLNDTPFHDEAVIQEHIEAGITLADAVNFLVERYELVRTDRKGF
TWQNQAPFLTATNILRARRATGLMNK

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12074.84 Da        Isoelectric Point: 5.9507

>AT266244 WP_269129794.1 NZ_CP114062:c2967258-2966935 [Rouxiella badensis]
MALIPPHKWGLPSDITPRFGARLVQEGNCLYYLADRAELIGSFTSEQLQKLEQAFPLFITKLENMLHSGALNPHHQYQVE
VHLDELTCIADTRGSCGYVYIAIYPQA

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References