Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4686153..4686741 Replicon chromosome
Accession NZ_CP114035
Organism Pseudomonas putida strain GMI12077

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OZ911_RS21420 Protein ID WP_023047767.1
Coordinates 4686153..4686455 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OZ911_RS21425 Protein ID WP_016488543.1
Coordinates 4686448..4686741 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ911_RS21395 (OZ911_21395) 4682079..4682207 - 129 WP_009683677.1 PA1414 family protein -
OZ911_RS21400 (OZ911_21400) 4682332..4683225 - 894 WP_016488538.1 LysR family transcriptional regulator -
OZ911_RS21405 (OZ911_21405) 4683332..4684501 + 1170 WP_070086856.1 MFS transporter -
OZ911_RS21410 (OZ911_21410) 4684549..4685475 - 927 WP_023047766.1 DMT family transporter -
OZ911_RS21415 (OZ911_21415) 4685582..4685977 - 396 WP_016498447.1 hypothetical protein -
OZ911_RS21420 (OZ911_21420) 4686153..4686455 + 303 WP_023047767.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZ911_RS21425 (OZ911_21425) 4686448..4686741 + 294 WP_016488543.1 putative addiction module antidote protein Antitoxin
OZ911_RS21430 (OZ911_21430) 4686831..4687103 + 273 WP_016488544.1 hypothetical protein -
OZ911_RS21435 (OZ911_21435) 4687225..4688586 - 1362 WP_023047768.1 DEAD/DEAH box helicase -
OZ911_RS21440 (OZ911_21440) 4688690..4689991 + 1302 WP_016488546.1 mechanosensitive ion channel family protein -
OZ911_RS21445 (OZ911_21445) 4690100..4691035 - 936 WP_023047769.1 AEC family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(6-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11337.04 Da        Isoelectric Point: 10.8638

>T266219 WP_023047767.1 NZ_CP114035:4686153-4686455 [Pseudomonas putida]
MKKIESSSFRHWVTGLRDLSARARIISRINRLMEGLPGDGSPVGHGVSELKIHYGPGYRVYFHQTGSTFVILLCGGDKSS
QKRDIKVAHQILRSWRMQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10446.88 Da        Isoelectric Point: 5.0637

>AT266219 WP_016488543.1 NZ_CP114035:4686448-4686741 [Pseudomonas putida]
MTETFSEFDPAAYLTTPEAIAQFMTDALETGDASYVAKAVGVVARAKGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMTARPHLAG

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References