Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 3737573..3738138 Replicon chromosome
Accession NZ_CP114029
Organism Jiella sp. HL-NP1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OH818_RS19035 Protein ID WP_268880043.1
Coordinates 3737573..3737947 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OH818_RS19040 Protein ID WP_233717942.1
Coordinates 3737947..3738138 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH818_RS19015 (OH818_19025) 3733507..3734243 - 737 Protein_3538 response regulator transcription factor -
OH818_RS19020 (OH818_19030) 3735022..3735432 + 411 WP_268880040.1 hypothetical protein -
OH818_RS19025 (OH818_19035) 3735669..3736340 - 672 WP_268880041.1 DUF1045 domain-containing protein -
OH818_RS19030 (OH818_19040) 3736670..3737542 + 873 WP_268880042.1 D-alanyl-D-alanine carboxypeptidase family protein -
OH818_RS19035 (OH818_19045) 3737573..3737947 - 375 WP_268880043.1 VapC toxin family PIN domain ribonuclease Toxin
OH818_RS19040 (OH818_19050) 3737947..3738138 - 192 WP_233717942.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OH818_RS19045 (OH818_19055) 3738320..3739525 - 1206 WP_268880044.1 translocation/assembly module TamB domain-containing protein -
OH818_RS19050 (OH818_19060) 3739554..3739778 + 225 WP_268880045.1 hypothetical protein -
OH818_RS19055 (OH818_19065) 3739906..3740505 - 600 WP_268880046.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13902.18 Da        Isoelectric Point: 5.1138

>T266214 WP_268880043.1 NZ_CP114029:c3737947-3737573 [Jiella sp. HL-NP1]
MIIADTSIWVDHLRLGDDVLADLLLANQIAGHPYVIAELALGSIRDRDKFLAMIEGLPTVLPTPLPDLREHIEQHRLYRR
GIGFVDVALVTICLSDPNLRLWTRDKRLASIALELQIAFSPQAD

Download         Length: 375 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7004.99 Da        Isoelectric Point: 6.3087

>AT266214 WP_233717942.1 NZ_CP114029:c3738138-3737947 [Jiella sp. HL-NP1]
MRTTVTLDDELLRRAVALTGNTERTALLREALTALIERESGRKLAALGGTEPDFEAPPRRRLD

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References