Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 637072..637703 Replicon chromosome
Accession NZ_CP114029
Organism Jiella sp. HL-NP1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OH818_RS04320 Protein ID WP_268881926.1
Coordinates 637072..637470 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OH818_RS04325 Protein ID WP_268881927.1
Coordinates 637470..637703 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH818_RS04305 (OH818_04320) 633055..634069 + 1015 Protein_625 alpha-ketoacid dehydrogenase subunit beta -
OH818_RS04310 (OH818_04325) 634071..635468 + 1398 WP_268881924.1 dihydrolipoamide acetyltransferase family protein -
OH818_RS04315 (OH818_04330) 635465..636862 + 1398 WP_268881925.1 dihydrolipoyl dehydrogenase -
OH818_RS04320 (OH818_04335) 637072..637470 - 399 WP_268881926.1 type II toxin-antitoxin system VapC family toxin Toxin
OH818_RS04325 (OH818_04340) 637470..637703 - 234 WP_268881927.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OH818_RS04330 (OH818_04345) 637827..638183 - 357 WP_268881928.1 tRNA-binding protein -
OH818_RS04335 (OH818_04350) 638235..639041 - 807 WP_268883609.1 pyrroline-5-carboxylate reductase -
OH818_RS04340 (OH818_04355) 639058..639558 - 501 WP_268881929.1 YbjN domain-containing protein -
OH818_RS04345 (OH818_04360) 639842..640117 - 276 WP_268881930.1 accessory factor UbiK family protein -
OH818_RS04350 (OH818_04365) 640346..641236 + 891 WP_268881931.1 prolipoprotein diacylglyceryl transferase -
OH818_RS04355 (OH818_04370) 641233..642336 + 1104 WP_268881932.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14818.13 Da        Isoelectric Point: 7.7727

>T266212 WP_268881926.1 NZ_CP114029:c637470-637072 [Jiella sp. HL-NP1]
MLAYMLDTNICIHVMKTYPPQVREKFNALAEQLCISSITLGELHYGAQKSARCAKNLTAIEHFVARLEVLPFADKAAVHY
GQLRAELERAGTPCGPHDMQIGAHARSEGLIVVTNNRREFDRMPGLRAENWL

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8685.82 Da        Isoelectric Point: 5.0490

>AT266212 WP_268881927.1 NZ_CP114029:c637703-637470 [Jiella sp. HL-NP1]
MTSTTIFTSNRSQAVRLPKAVAFPDTVDQVDILKIGSSRLIVPKGRRWDDLFLGGPRVSEDFLGERQQPETEDREPL

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References