Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
| Location | 219816..221324 | Replicon | chromosome |
| Accession | NZ_CP113974 | ||
| Organism | Pseudomonas aeruginosa strain M6A146 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | Q9HYX1 |
| Locus tag | OZ175_RS01030 | Protein ID | WP_003119682.1 |
| Coordinates | 219816..220403 (+) | Length | 196 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | OZ175_RS01035 | Protein ID | WP_268858489.1 |
| Coordinates | 220470..221324 (+) | Length | 285 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OZ175_RS01025 (OZ175_01025) | 216071..219550 | - | 3480 | WP_003117605.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
| OZ175_RS01030 (OZ175_01030) | 219816..220403 | + | 588 | WP_003119682.1 | GNAT family protein | Toxin |
| OZ175_RS01035 (OZ175_01035) | 220470..221324 | + | 855 | WP_268858489.1 | AraC family transcriptional regulator | Antitoxin |
| OZ175_RS01040 (OZ175_01040) | 221421..223586 | + | 2166 | WP_003115567.1 | TonB-dependent receptor family protein | - |
| OZ175_RS01045 (OZ175_01045) | 223761..225635 | + | 1875 | WP_003117607.1 | MFS transporter | - |
| OZ175_RS01050 (OZ175_01050) | 225696..225905 | - | 210 | WP_003115568.1 | cold-shock protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 196 a.a. Molecular weight: 21901.23 Da Isoelectric Point: 9.8676
>T266199 WP_003119682.1 NZ_CP113974:219816-220403 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
Download Length: 588 bp
Antitoxin
Download Length: 285 a.a. Molecular weight: 31897.17 Da Isoelectric Point: 7.5295
>AT266199 WP_268858489.1 NZ_CP113974:220470-221324 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHSGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETMLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEAALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHSGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETMLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEAALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE
Download Length: 855 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|