Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pezAT/zeta-ParD |
| Location | 635756..636726 | Replicon | plasmid unnamed |
| Accession | NZ_CP113952 | ||
| Organism | Rhodococcus sp. JS3073 | ||
Toxin (Protein)
| Gene name | pezT | Uniprot ID | - |
| Locus tag | OYT95_RS40775 | Protein ID | WP_268793197.1 |
| Coordinates | 635756..636346 (-) | Length | 197 a.a. |
Antitoxin (Protein)
| Gene name | pezA | Uniprot ID | - |
| Locus tag | OYT95_RS40780 | Protein ID | WP_268793153.1 |
| Coordinates | 636343..636726 (-) | Length | 128 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OYT95_RS40760 (OYT95_40760) | 630957..632393 | + | 1437 | WP_268793194.1 | hypothetical protein | - |
| OYT95_RS40765 (OYT95_40765) | 632521..634065 | + | 1545 | WP_268793195.1 | patatin-like phospholipase family protein | - |
| OYT95_RS40770 (OYT95_40770) | 634457..634768 | - | 312 | WP_268793196.1 | hypothetical protein | - |
| OYT95_RS40775 (OYT95_40775) | 635756..636346 | - | 591 | WP_268793197.1 | zeta toxin family protein | Toxin |
| OYT95_RS40780 (OYT95_40780) | 636343..636726 | - | 384 | WP_268793153.1 | hypothetical protein | Antitoxin |
| OYT95_RS40785 (OYT95_40785) | 637387..638391 | - | 1005 | WP_268793198.1 | acyl-CoA dehydrogenase family protein | - |
| OYT95_RS40790 (OYT95_40790) | 638650..639951 | - | 1302 | WP_268793199.1 | Rep protein | - |
| OYT95_RS40795 (OYT95_40795) | 640330..640647 | - | 318 | WP_268793200.1 | hypothetical protein | - |
| OYT95_RS40800 (OYT95_40800) | 640644..641288 | - | 645 | WP_268793201.1 | hypothetical protein | - |
| OYT95_RS40805 (OYT95_40805) | 641447..641704 | - | 258 | WP_268793202.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..1387438 | 1387438 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 197 a.a. Molecular weight: 21738.71 Da Isoelectric Point: 8.0085
>T266191 WP_268793197.1 NZ_CP113952:c636346-635756 [Rhodococcus sp. JS3073]
VKRLDLVVGCNGAGKSTFVAFTLAPLLPASPFVNADEIAKQRWPANPAAHSYEAAEIAAKTRAHLLTLGKSFIAETVFSH
RSKLELIDEARTHDYTVILHVLMIPEELAVQRVRYRVRAGGHDVPEDKIRQRYHRLWGLLAQAFPRCDHVSVYDNSASTG
PRIVAQFTDGHLVGEATWPAWTPAELTSHTSRGEQP
VKRLDLVVGCNGAGKSTFVAFTLAPLLPASPFVNADEIAKQRWPANPAAHSYEAAEIAAKTRAHLLTLGKSFIAETVFSH
RSKLELIDEARTHDYTVILHVLMIPEELAVQRVRYRVRAGGHDVPEDKIRQRYHRLWGLLAQAFPRCDHVSVYDNSASTG
PRIVAQFTDGHLVGEATWPAWTPAELTSHTSRGEQP
Download Length: 591 bp
Antitoxin
Download Length: 128 a.a. Molecular weight: 13636.13 Da Isoelectric Point: 4.9627
>AT266191 WP_268793153.1 NZ_CP113952:c636726-636343 [Rhodococcus sp. JS3073]
MHSTGDKVTRLAADLVASAMAEGERQHRTGRQQLEHWARVGRAVSSRQTAARRRVEDALAGRLPIGELGPEEGTVFNAEI
NAAIEEQLATTDYGAALAAQGVTTVALSEDGQIIEYRPDGTRTVLPE
MHSTGDKVTRLAADLVASAMAEGERQHRTGRQQLEHWARVGRAVSSRQTAARRRVEDALAGRLPIGELGPEEGTVFNAEI
NAAIEEQLATTDYGAALAAQGVTTVALSEDGQIIEYRPDGTRTVLPE
Download Length: 384 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|