Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pezAT/zeta-ParD |
| Location | 568400..569370 | Replicon | plasmid unnamed |
| Accession | NZ_CP113952 | ||
| Organism | Rhodococcus sp. JS3073 | ||
Toxin (Protein)
| Gene name | pezT | Uniprot ID | - |
| Locus tag | OYT95_RS40520 | Protein ID | WP_268793152.1 |
| Coordinates | 568400..568990 (-) | Length | 197 a.a. |
Antitoxin (Protein)
| Gene name | pezA | Uniprot ID | - |
| Locus tag | OYT95_RS40525 | Protein ID | WP_268793153.1 |
| Coordinates | 568987..569370 (-) | Length | 128 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OYT95_RS40495 (OYT95_40495) | 563606..563911 | - | 306 | WP_268793149.1 | hypothetical protein | - |
| OYT95_RS40500 (OYT95_40500) | 564218..565483 | - | 1266 | WP_268793150.1 | acyl-CoA dehydrogenase family protein | - |
| OYT95_RS40505 (OYT95_40505) | 565560..567008 | - | 1449 | WP_268793151.1 | aldehyde dehydrogenase family protein | - |
| OYT95_RS40510 (OYT95_40510) | 567900..567971 | + | 72 | Protein_482 | DUF4193 family protein | - |
| OYT95_RS40515 (OYT95_40515) | 568215..568342 | - | 128 | Protein_483 | DUF4193 family protein | - |
| OYT95_RS40520 (OYT95_40520) | 568400..568990 | - | 591 | WP_268793152.1 | zeta toxin family protein | Toxin |
| OYT95_RS40525 (OYT95_40525) | 568987..569370 | - | 384 | WP_268793153.1 | hypothetical protein | Antitoxin |
| OYT95_RS40530 (OYT95_40530) | 570002..570256 | - | 255 | WP_268793154.1 | hypothetical protein | - |
| OYT95_RS40535 (OYT95_40535) | 570691..572031 | - | 1341 | WP_268793155.1 | MFS transporter | - |
| OYT95_RS40540 (OYT95_40540) | 572651..573232 | - | 582 | WP_268793156.1 | NAD-dependent epimerase/dehydratase family protein | - |
| OYT95_RS40545 (OYT95_40545) | 573479..573697 | - | 219 | WP_081315626.1 | SDR family oxidoreductase | - |
| OYT95_RS40550 (OYT95_40550) | 573747..574232 | - | 486 | WP_268793157.1 | carboxymuconolactone decarboxylase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..1387438 | 1387438 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 197 a.a. Molecular weight: 21747.72 Da Isoelectric Point: 8.0227
>T266190 WP_268793152.1 NZ_CP113952:c568990-568400 [Rhodococcus sp. JS3073]
VKRLDLVVGCNGAGKSTFVAFTLAPLLPASPFVNADEIAKQRWPANPAAHSYEAAEIAAKTRAHLLTLGKSFIAETVFSH
RSKLELIDEARTHDYTVILHVLMIPEELAVQRVRYRVRAGGHDVPEDKIRQRYHRLWGLLAQAFPRCDHVSVYDNSASTG
PRIVAQFTDGHLVGEATWPAWTPAELTSHTSRGEHP
VKRLDLVVGCNGAGKSTFVAFTLAPLLPASPFVNADEIAKQRWPANPAAHSYEAAEIAAKTRAHLLTLGKSFIAETVFSH
RSKLELIDEARTHDYTVILHVLMIPEELAVQRVRYRVRAGGHDVPEDKIRQRYHRLWGLLAQAFPRCDHVSVYDNSASTG
PRIVAQFTDGHLVGEATWPAWTPAELTSHTSRGEHP
Download Length: 591 bp
Antitoxin
Download Length: 128 a.a. Molecular weight: 13636.13 Da Isoelectric Point: 4.9627
>AT266190 WP_268793153.1 NZ_CP113952:c569370-568987 [Rhodococcus sp. JS3073]
MHSTGDKVTRLAADLVASAMAEGERQHRTGRQQLEHWARVGRAVSSRQTAARRRVEDALAGRLPIGELGPEEGTVFNAEI
NAAIEEQLATTDYGAALAAQGVTTVALSEDGQIIEYRPDGTRTVLPE
MHSTGDKVTRLAADLVASAMAEGERQHRTGRQQLEHWARVGRAVSSRQTAARRRVEDALAGRLPIGELGPEEGTVFNAEI
NAAIEEQLATTDYGAALAAQGVTTVALSEDGQIIEYRPDGTRTVLPE
Download Length: 384 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|