Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1323530..1324063 Replicon chromosome
Accession NZ_CP113946
Organism Lactobacillus sp. ESL0677

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX76_RS06430 Protein ID WP_277164038.1
Coordinates 1323791..1324063 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX76_RS06425 Protein ID WP_277164037.1
Coordinates 1323530..1323787 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX76_RS06410 (OZX76_06410) 1319075..1320037 - 963 WP_277178823.1 D-2-hydroxyacid dehydrogenase -
OZX76_RS06415 (OZX76_06415) 1320922..1322109 + 1188 WP_277178825.1 restriction endonuclease subunit S -
OZX76_RS06420 (OZX76_06420) 1322465..1323385 - 921 WP_277178828.1 site-specific integrase -
OZX76_RS06425 (OZX76_06425) 1323530..1323787 + 258 WP_277164037.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX76_RS06430 (OZX76_06430) 1323791..1324063 + 273 WP_277164038.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX76_RS06435 (OZX76_06435) 1324124..1325266 - 1143 WP_277178830.1 restriction endonuclease subunit S -
OZX76_RS06440 (OZX76_06440) 1325259..1326914 - 1656 WP_277178832.1 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10505.31 Da        Isoelectric Point: 9.9839

>T266185 WP_277164038.1 NZ_CP113946:1323791-1324063 [Lactobacillus sp. ESL0677]
MLNIKVTAKFRKDVKRCNKQGLPMTQLKLVIHELEQNHVLPSNYKNHALDGTYSNYLECHIKPDWLLIYQITQTTLALIR
TGSHAELFKK

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9749.08 Da        Isoelectric Point: 4.6135

>AT266185 WP_277164037.1 NZ_CP113946:1323530-1323787 [Lactobacillus sp. ESL0677]
MNKTLQARMDGKLMDEAEGILKDLGLNRSTALKIFYQQIVWNNGLPFAVKKPEIPNEETLDAMHEDLSKTKTYDNSDELW
HDLGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References