Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1102986..1103519 Replicon chromosome
Accession NZ_CP113945
Organism Lactobacillus sp. ESL0680

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX58_RS05250 Protein ID WP_277140549.1
Coordinates 1103247..1103519 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX58_RS05245 Protein ID WP_277140548.1
Coordinates 1102986..1103243 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX58_RS05230 (OZX58_05230) 1098614..1099576 - 963 WP_277140545.1 D-2-hydroxyacid dehydrogenase -
OZX58_RS05235 (OZX58_05235) 1100484..1101554 + 1071 WP_277140546.1 restriction endonuclease subunit S -
OZX58_RS05240 (OZX58_05240) 1101921..1102841 - 921 WP_277140547.1 site-specific integrase -
OZX58_RS05245 (OZX58_05245) 1102986..1103243 + 258 WP_277140548.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX58_RS05250 (OZX58_05250) 1103247..1103519 + 273 WP_277140549.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX58_RS05255 (OZX58_05255) 1103582..1104790 - 1209 WP_277140550.1 restriction endonuclease subunit S -
OZX58_RS05260 (OZX58_05260) 1104783..1106438 - 1656 WP_277140551.1 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10535.34 Da        Isoelectric Point: 10.0104

>T266184 WP_277140549.1 NZ_CP113945:1103247-1103519 [Lactobacillus sp. ESL0680]
MLNIKVTAKFRKDVKRCNRQGLPMTQLKLVIHELEQNHVLSSNYKNHALDGTYSNYLECHIKPDWLLIYQITQITLALIR
TGSHAELFKK

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9765.12 Da        Isoelectric Point: 4.6135

>AT266184 WP_277140548.1 NZ_CP113945:1102986-1103243 [Lactobacillus sp. ESL0680]
MNKTLQARMDGKLMDEAEGILKDLGLNRSTALKIFYQQIVWNNGLPFAVKKPEILNEETLDAMHEDLSKTKTYDNSDELW
HDLGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References