Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1481662..1482192 Replicon chromosome
Accession NZ_CP113943
Organism Lactobacillus sp. ESL0681

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX59_RS07060 Protein ID WP_277125603.1
Coordinates 1481926..1482192 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX59_RS07055 Protein ID WP_277125601.1
Coordinates 1481662..1481922 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX59_RS07045 (OZX59_07045) 1476890..1479304 + 2415 WP_277125597.1 SLAP domain-containing protein -
OZX59_RS07050 (OZX59_07050) 1479662..1481491 + 1830 WP_277125599.1 SLAP domain-containing protein -
OZX59_RS07055 (OZX59_07055) 1481662..1481922 + 261 WP_277125601.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX59_RS07060 (OZX59_07060) 1481926..1482192 + 267 WP_277125603.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX59_RS07065 (OZX59_07065) 1482427..1483269 + 843 WP_277125605.1 hypothetical protein -
OZX59_RS07070 (OZX59_07070) 1483515..1484000 + 486 WP_277125606.1 sigma-70 family RNA polymerase sigma factor -
OZX59_RS07075 (OZX59_07075) 1484123..1485337 + 1215 WP_277125608.1 SLAP domain-containing protein -
OZX59_RS07080 (OZX59_07080) 1485373..1486512 + 1140 WP_277125611.1 SLAP domain-containing protein -
OZX59_RS07085 (OZX59_07085) 1486636..1486899 + 264 WP_277125612.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10413.04 Da        Isoelectric Point: 7.9271

>T266182 WP_277125603.1 NZ_CP113943:1481926-1482192 [Lactobacillus sp. ESL0681]
MFQIKATGKFKRDVKRCNKQGLEMDLLKKVVHELELGHELDRQYKNHGLSGNYDNFLECHIKPDWLLIYRVEQDTLILIR
TGSHADLF

Download         Length: 267 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9829.33 Da        Isoelectric Point: 5.8212

>AT266182 WP_277125601.1 NZ_CP113943:1481662-1481922 [Lactobacillus sp. ESL0681]
MMNKTLQARMDSQLMDKAEGILKDLGLNRSTALKMFYQQIVLNDGLPFEVKKPDKPNNATLQAMHEDLSKTKAYNDSKEL
WDELGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References