266181

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 3777..4317 Replicon chromosome
Accession NZ_CP113943
Organism Lactobacillus sp. ESL0681

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX59_RS00045 Protein ID WP_277126107.1
Coordinates 3777..4052 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX59_RS00050 Protein ID WP_277126108.1
Coordinates 4039..4317 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX59_RS00005 (OZX59_00005) 5..808 + 804 WP_277126100.1 DnaA/Hda family protein -
OZX59_RS00010 (OZX59_00010) 809..1264 + 456 WP_277126101.1 single-stranded DNA-binding protein -
OZX59_RS00015 (OZX59_00015) 1278..1565 + 288 WP_277126102.1 DUF6275 family protein -
OZX59_RS00020 (OZX59_00020) 1762..2232 + 471 WP_277126103.1 hypothetical protein -
OZX59_RS00025 (OZX59_00025) 2225..2605 + 381 WP_277127019.1 VRR-NUC domain-containing protein -
OZX59_RS00030 (OZX59_00030) 2595..2792 + 198 WP_277126104.1 hypothetical protein -
OZX59_RS00035 (OZX59_00035) 2773..3261 + 489 WP_277126105.1 hypothetical protein -
OZX59_RS00040 (OZX59_00040) 3278..3733 + 456 WP_277126106.1 ArpU family phage packaging/lysis transcriptional regulator -
OZX59_RS00045 (OZX59_00045) 3777..4052 - 276 WP_277126107.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX59_RS00050 (OZX59_00050) 4039..4317 - 279 WP_277126108.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX59_RS00055 (OZX59_00055) 4718..5626 + 909 WP_277126109.1 hypothetical protein -
OZX59_RS00060 (OZX59_00060) 5672..5980 + 309 WP_277126110.1 hypothetical protein -
OZX59_RS00065 (OZX59_00065) 6034..6468 + 435 WP_277126111.1 terminase small subunit -
OZX59_RS00070 (OZX59_00070) 6461..7708 + 1248 WP_277126112.1 PBSX family phage terminase large subunit -
OZX59_RS00075 (OZX59_00075) 7699..9123 + 1425 WP_277126113.1 phage portal protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5..29529 29524


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-74)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10465.20 Da        Isoelectric Point: 10.5117

>T266181 WP_277126107.1 NZ_CP113943:c4052-3777 [Lactobacillus sp. ESL0681]
MYKVKQSRKFKKSAKQAIKQGKDINKLVAAVKAIVTNTISPNYHDHELKGKWQGTRELHIEPDWLLTYKIKGNELILYLV
DTGSHSQLFGK

Download         Length: 276 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10518.75 Da        Isoelectric Point: 4.1453

>AT266181 WP_277126108.1 NZ_CP113943:c4317-4039 [Lactobacillus sp. ESL0681]
MSTDVSKKTNLNVKIDTNLKNEADLVFKDMGLTLSAAITMFLKRSVDDRELPFQPRVTTEMDQALDEINSGNVESFDSVE
DWEEDLRKYVQS

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References