Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 752805..753676 Replicon chromosome
Accession NZ_CP113942
Organism Bifidobacterium sp. ESL0682

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX57_RS03180 Protein ID WP_277162682.1
Coordinates 753170..753676 (+) Length 169 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX57_RS03175 Protein ID WP_277162681.1
Coordinates 752805..753155 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX57_RS03150 (OZX57_03155) 747921..748892 + 972 WP_277162678.1 ABC transporter permease -
OZX57_RS03155 (OZX57_03160) 748952..749821 + 870 WP_277162918.1 ABC transporter permease -
OZX57_RS03160 (OZX57_03165) 749824..750612 + 789 WP_277162919.1 ABC transporter ATP-binding protein -
OZX57_RS03165 (OZX57_03170) 750605..751390 + 786 WP_277162679.1 dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein -
OZX57_RS03170 (OZX57_03175) 751490..752482 - 993 WP_277162680.1 NAD(P)-dependent oxidoreductase -
OZX57_RS03175 (OZX57_03180) 752805..753155 + 351 WP_277162681.1 damage-inducible protein J Antitoxin
OZX57_RS03180 (OZX57_03185) 753170..753676 + 507 WP_277162682.1 PIN domain-containing protein Toxin
OZX57_RS03185 (OZX57_03190) 753866..755909 + 2044 Protein_611 RecQ family ATP-dependent DNA helicase -
OZX57_RS03190 (OZX57_03195) 756100..757383 + 1284 WP_277162683.1 HRDC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-142)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18685.43 Da        Isoelectric Point: 4.6576

>T266180 WP_277162682.1 NZ_CP113942:753170-753676 [Bifidobacterium sp. ESL0682]
MIEEKRVVFDTNVLLDYLLTWRSGNANAIQLLRACSNSEMIKLLCVSLSLKDVDYISRSSFKKQFAGNESVVVQATVSNM
APKFGWHCVDDLLKIIALVVAVDQSTCKHALKLWDVHPDYEDDLIIAASRQANADMVVTGDQDLIKHFPDLCVSVEDALK
QIDGTDQG

Download         Length: 507 bp

>T266180 NZ_CP113942:753170-753676 [Bifidobacterium sp. ESL0682]
ATGATTGAAGAAAAACGAGTGGTTTTCGATACGAATGTGCTGCTGGACTATCTTCTCACCTGGCGTTCTGGTAACGCGAA
TGCTATACAACTTCTGCGTGCCTGTTCGAATTCGGAAATGATTAAGTTGCTTTGTGTCTCTCTATCTTTAAAAGATGTTG
ACTATATCTCGAGGTCATCGTTTAAAAAACAATTTGCAGGCAATGAATCTGTAGTTGTACAGGCTACCGTTTCCAATATG
GCTCCTAAGTTCGGTTGGCATTGCGTTGATGATTTATTGAAAATAATTGCATTGGTGGTTGCAGTCGATCAATCAACTTG
TAAGCATGCTCTCAAGTTATGGGATGTTCATCCTGATTATGAAGATGATCTCATTATTGCCGCGTCGCGTCAGGCCAACG
CCGACATGGTGGTGACGGGGGATCAGGATTTAATCAAGCATTTCCCGGATTTGTGCGTCAGTGTTGAGGACGCATTGAAG
CAGATTGACGGAACGGACCAAGGCTAG

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 13293.81 Da        Isoelectric Point: 4.8512

>AT266180 WP_277162681.1 NZ_CP113942:752805-753155 [Bifidobacterium sp. ESL0682]
MSMVQMNVRIDSDVKDDVDEILKRKGKTPSSVVRELWDFIKDHGDTPDLQTKAEKANKEAEKQRRLKAIEDGATLWSRTL
KEAGLPDDGQHPWADMTYKGMRDAAYEDSVNEYAHE

Download         Length: 351 bp

>AT266180 NZ_CP113942:752805-753155 [Bifidobacterium sp. ESL0682]
ATGTCGATGGTACAGATGAACGTCCGTATCGATTCCGATGTGAAGGACGACGTCGACGAGATACTCAAGCGCAAGGGGAA
GACCCCAAGTTCCGTGGTGCGTGAGCTGTGGGACTTCATCAAGGATCATGGGGATACTCCGGATTTGCAGACTAAGGCTG
AAAAAGCGAATAAGGAAGCCGAAAAGCAGCGCAGACTCAAAGCGATAGAGGATGGTGCGACTTTATGGTCTCGAACGTTG
AAAGAGGCGGGTTTGCCTGATGACGGTCAACATCCTTGGGCGGATATGACGTATAAGGGAATGCGCGATGCGGCTTATGA
AGATTCAGTCAATGAATACGCACATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References