Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/PIN-DinJ
Location 857052..857908 Replicon chromosome
Accession NZ_CP113939
Organism Bifidobacterium sp. ESL0690

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX62_RS03430 Protein ID WP_277176612.1
Coordinates 857414..857908 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX62_RS03425 Protein ID WP_277176611.1
Coordinates 857052..857417 (+) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX62_RS03400 (OZX62_03400) 852123..852908 + 786 WP_277176604.1 dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein -
OZX62_RS03405 (OZX62_03405) 853049..854041 - 993 WP_277176606.1 NAD(P)-dependent oxidoreductase -
OZX62_RS03410 (OZX62_03410) 854161..854364 - 204 WP_277176607.1 helix-turn-helix transcriptional regulator -
OZX62_RS03415 (OZX62_03415) 854351..854845 - 495 WP_277176609.1 hypothetical protein -
OZX62_RS03420 (OZX62_03420) 855105..856913 + 1809 WP_277176610.1 alpha-glucosidase -
OZX62_RS03425 (OZX62_03425) 857052..857417 + 366 WP_277176611.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX62_RS03430 (OZX62_03430) 857414..857908 + 495 WP_277176612.1 PIN domain-containing protein Toxin
OZX62_RS03435 (OZX62_03435) 858026..858649 + 624 WP_277176613.1 isochorismatase family protein -
OZX62_RS03440 (OZX62_03440) 858649..860640 + 1992 WP_277176614.1 DNA helicase RecQ -
OZX62_RS03445 (OZX62_03445) 860717..861190 + 474 WP_277176615.1 ASCH domain-containing protein -
OZX62_RS03450 (OZX62_03450) 861329..862660 + 1332 WP_277176616.1 HRDC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-141)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-60)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18221.94 Da        Isoelectric Point: 4.4434

>T266175 WP_277176612.1 NZ_CP113939:857414-857908 [Bifidobacterium sp. ESL0690]
MKESKRNIVFDTNILIDIVMHRSLRESAALKLMDVCANQTLNPMCVALSLKDVDYIVKVNTKRDFKDAMAGVEQATVQQL
VAQVGWNSVESIMEVCEVVAVDGQVCKNALKLRSAHPDYEDDLIIAASRQANADMVVTGDQDLIKHFPDLCVSVEDALKQ
IEED

Download         Length: 495 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 14034.85 Da        Isoelectric Point: 4.4845

>AT266175 WP_277176611.1 NZ_CP113939:857052-857417 [Bifidobacterium sp. ESL0690]
MSMVQMNVRIDADLKDEVDEILKRIGKTPSSVIRELWDYIQDSGEIPDLETAREKKDQELEKRKKLEKIDNMSGIVPRTL
SDMGLIGRGDDPFKSMSAKELHDYADEQRYEDYIQESVAVR

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References