Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 21337..21925 Replicon plasmid unnamed5
Accession NZ_CP113936
Organism Acinetobacter sp. ESL0695

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX61_RS12585 Protein ID WP_191103926.1
Coordinates 21629..21925 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX61_RS12580 Protein ID WP_191103925.1
Coordinates 21337..21627 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX61_RS12555 (OZX61_12555) 16821..17459 - 639 WP_277095787.1 hypothetical protein -
OZX61_RS12560 (OZX61_12560) 17449..18852 - 1404 WP_277095788.1 AAA family ATPase -
OZX61_RS12565 (OZX61_12565) 19485..20090 - 606 WP_277095769.1 DUF4326 domain-containing protein -
OZX61_RS12570 (OZX61_12570) 20093..20533 - 441 WP_277095770.1 DUF488 domain-containing protein -
OZX61_RS12575 (OZX61_12575) 20547..21188 - 642 WP_277095771.1 hypothetical protein -
OZX61_RS12580 (OZX61_12580) 21337..21627 - 291 WP_191103925.1 putative addiction module antidote protein Antitoxin
OZX61_RS12585 (OZX61_12585) 21629..21925 - 297 WP_191103926.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZX61_RS12590 (OZX61_12590) 22428..22550 - 123 WP_277095789.1 hypothetical protein -
OZX61_RS12595 (OZX61_12595) 23110..23682 - 573 WP_277095772.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..34963 34963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(7-93)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11554.31 Da        Isoelectric Point: 8.5275

>T266173 WP_191103926.1 NZ_CP113936:c21925-21629 [Acinetobacter sp. ESL0695]
MIEIKRLPEFDEWLDGLKDNMTRIRLNRRLDKVQRGNWGDIKPLQEGVWEMREFFGAGWRMYYIQHGDVVIVMLGGGEKS
TQSKDIDRAVKLSKTLEN

Download         Length: 297 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10529.19 Da        Isoelectric Point: 5.6088

>AT266173 WP_191103925.1 NZ_CP113936:c21627-21337 [Acinetobacter sp. ESL0695]
MVKVADLPSFDMAESLKTEEDIVIYLNMVLEDNDPAELAHALGVIAKARGMTQIAKEAGIGREALYKALRHDSAPRFDTI
NRVVNALGLKITVQHV

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References