Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 43484..44012 Replicon plasmid unnamed4
Accession NZ_CP113935
Organism Acinetobacter sp. ESL0695

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX61_RS12295 Protein ID WP_277095764.1
Coordinates 43484..43777 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX61_RS12300 Protein ID WP_277095765.1
Coordinates 43767..44012 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX61_RS12265 (OZX61_12265) 39384..40073 + 690 WP_277095759.1 hypothetical protein -
OZX61_RS12270 (OZX61_12270) 40235..40378 + 144 Protein_34 RepB family plasmid replication initiator protein -
OZX61_RS12275 (OZX61_12275) 40397..41242 - 846 WP_277095760.1 nitroreductase family protein -
OZX61_RS12280 (OZX61_12280) 41379..42278 + 900 WP_277095761.1 LysR family transcriptional regulator -
OZX61_RS12285 (OZX61_12285) 42384..42767 - 384 WP_277095762.1 VOC family protein -
OZX61_RS12290 (OZX61_12290) 42904..43410 - 507 WP_277095763.1 hypothetical protein -
OZX61_RS12295 (OZX61_12295) 43484..43777 - 294 WP_277095764.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZX61_RS12300 (OZX61_12300) 43767..44012 - 246 WP_277095765.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX61_RS12305 (OZX61_12305) 44559..44885 - 327 WP_277095766.1 hypothetical protein -
OZX61_RS12310 (OZX61_12310) 45125..45256 + 132 WP_277095767.1 hypothetical protein -
OZX61_RS12315 (OZX61_12315) 45633..46433 + 801 WP_277095705.1 hypothetical protein -
OZX61_RS12320 (OZX61_12320) 46559..46704 - 146 Protein_44 transcriptional regulator -
OZX61_RS12325 (OZX61_12325) 46967..48109 - 1143 WP_277095706.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..90863 90863


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11212.30 Da        Isoelectric Point: 10.5837

>T266172 WP_277095764.1 NZ_CP113935:c43777-43484 [Acinetobacter sp. ESL0695]
MTYKLLRHKDFASEWENLPSAIRDQLKKKLSKIIQQPHVPKNILRGDLAGCYKIKLLKAGVRLVYQVRDDQVIILLITVG
KRADNIVYNEAKKRIGD

Download         Length: 294 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9192.59 Da        Isoelectric Point: 4.6258

>AT266172 WP_277095765.1 NZ_CP113935:c44012-43767 [Acinetobacter sp. ESL0695]
MATVNFRVNEALKEKSYSILREHGIAPTELFTNVLEYIATTGKIPVQKALLSEEDTELLAIVRKRINDPKGMFEEITLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References