Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-DinJ
Location 2457223..2457754 Replicon chromosome
Accession NZ_CP113925
Organism Bifidobacterium sp. ESL0728

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OZX67_RS09155 Protein ID WP_277142816.1
Coordinates 2457473..2457754 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX67_RS09150 Protein ID WP_277142814.1
Coordinates 2457223..2457480 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX67_RS09130 (OZX67_09130) 2452501..2452704 - 204 WP_277142805.1 hypothetical protein -
OZX67_RS09135 (OZX67_09135) 2453099..2454649 - 1551 WP_277142807.1 amino acid permease -
OZX67_RS09140 (OZX67_09140) 2455193..2455465 + 273 WP_277142809.1 hypothetical protein -
OZX67_RS09145 (OZX67_09145) 2455462..2457009 + 1548 WP_277142812.1 amino acid permease -
OZX67_RS09150 (OZX67_09150) 2457223..2457480 + 258 WP_277142814.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX67_RS09155 (OZX67_09155) 2457473..2457754 + 282 WP_277142816.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX67_RS09160 (OZX67_09160) 2457953..2458324 - 372 WP_277142818.1 hypothetical protein -
OZX67_RS09165 (OZX67_09165) 2458846..2459901 - 1056 WP_277142821.1 ketol-acid reductoisomerase -
OZX67_RS09170 (OZX67_09170) 2460270..2461568 - 1299 WP_277145072.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11081.78 Da        Isoelectric Point: 10.2227

>T266169 WP_277142816.1 NZ_CP113925:2457473-2457754 [Bifidobacterium sp. ESL0728]
MLDSVFRTSQFKRDFKALVRKHYNPETMRAAVSALMGQNKDLLRTKYRDHPLTGEWKGYREIHLEGDWLVIYRIKKTELQ
LVLTRTGSHDDLF

Download         Length: 282 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9672.88 Da        Isoelectric Point: 5.5882

>AT266169 WP_277142814.1 NZ_CP113925:2457223-2457480 [Bifidobacterium sp. ESL0728]
MTTTTISFRTDKTIKEQAKQLYAEMGMDLSTAINIFLRQSITDNAMPFRVTRDKPENIAARGQAEHHEGKTFQSVDDLME
DLNHA

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References