Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-DinJ
Location 2389374..2389905 Replicon chromosome
Accession NZ_CP113925
Organism Bifidobacterium sp. ESL0728

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OZX67_RS08940 Protein ID WP_277142730.1
Coordinates 2389618..2389905 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX67_RS08935 Protein ID WP_277142728.1
Coordinates 2389374..2389625 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX67_RS08925 (OZX67_08925) 2385144..2386208 + 1065 WP_277142723.1 2,3-butanediol dehydrogenase -
OZX67_RS08930 (OZX67_08930) 2386893..2388830 + 1938 WP_277142725.1 leucine-rich repeat domain-containing protein -
OZX67_RS08935 (OZX67_08935) 2389374..2389625 + 252 WP_277142728.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX67_RS08940 (OZX67_08940) 2389618..2389905 + 288 WP_277142730.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX67_RS08945 (OZX67_08945) 2389990..2392185 + 2196 WP_277142732.1 hypothetical protein -
OZX67_RS08950 (OZX67_08950) 2392178..2393314 + 1137 WP_277142734.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11211.16 Da        Isoelectric Point: 10.0633

>T266168 WP_277142730.1 NZ_CP113925:2389618-2389905 [Bifidobacterium sp. ESL0728]
MLKHVTRTGTFLKDVKKLKRKHFNLDKLDYVIQLLIKQDTAILIHEYNDHALKGNLRTFRELHIEPDWLLVYQIEHGTLT
LVLVETGSHKQLLGR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9290.53 Da        Isoelectric Point: 5.0323

>AT266168 WP_277142728.1 NZ_CP113925:2389374-2389625 [Bifidobacterium sp. ESL0728]
MSSATIAVRTDPEVKKEAQDVFKSIGLDMSGAINIFLRQVISDQGLPFQPKRNAFETRIQKAMNSGTRTFDNVDDLMDEL
RNA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References