Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-yefM/YoeB-RelB
Location 28828..29368 Replicon chromosome
Accession NZ_CP113921
Organism Lactobacillus sp. ESL0731

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag OZX69_RS00160 Protein ID WP_277143562.1
Coordinates 29102..29368 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OZX69_RS00155 Protein ID WP_277143560.1
Coordinates 28828..29121 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX69_RS00130 (OZX69_00130) 25497..25847 + 351 WP_277143551.1 type II toxin-antitoxin system RelE/ParE family toxin -
OZX69_RS00135 (OZX69_00135) 25840..26121 + 282 WP_277143552.1 helix-turn-helix transcriptional regulator -
OZX69_RS00140 (OZX69_00140) 26311..26976 - 666 WP_277143554.1 hypothetical protein -
OZX69_RS00145 (OZX69_00145) 27499..27657 - 159 WP_277143556.1 hypothetical protein -
OZX69_RS00150 (OZX69_00150) 27935..28726 + 792 WP_277143558.1 TraX family protein -
OZX69_RS00155 (OZX69_00155) 28828..29121 + 294 WP_277143560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OZX69_RS00160 (OZX69_00160) 29102..29368 + 267 WP_277143562.1 Txe/YoeB family addiction module toxin Toxin
OZX69_RS00165 (OZX69_00165) 29489..30403 + 915 WP_277143564.1 ABC transporter ATP-binding protein -
OZX69_RS00170 (OZX69_00170) 30403..31176 + 774 WP_277143566.1 ABC transporter permease -
OZX69_RS00175 (OZX69_00175) 31180..31824 + 645 WP_277143568.1 TetR/AcrR family transcriptional regulator -
OZX69_RS00180 (OZX69_00180) 31941..32804 + 864 WP_277143570.1 NAD(P)-dependent oxidoreductase -
OZX69_RS00185 (OZX69_00185) 32819..33670 + 852 WP_277143571.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10659.12 Da        Isoelectric Point: 7.8913

>T266166 WP_277143562.1 NZ_CP113921:29102-29368 [Lactobacillus sp. ESL0731]
MILSWTDESWDDYVYWQKQGDKKKIRRINKLIKDIERHPFEGLGKPEGLKHDLSGYWSRKIDAKDRIIYKCSVNELVIYS
CKDHYDDH

Download         Length: 267 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11367.61 Da        Isoelectric Point: 4.4954

>AT266166 WP_277143560.1 NZ_CP113921:28828-29121 [Lactobacillus sp. ESL0731]
MDAVNYSNFRKHLKDYFKQVNDHSEPLIVTNKEPEDNVVVMSKQEYDSLVETLDIESNKYLMAKIRNGQKQVDANRAVHH
ELIDPDYEVDTDDIKLD

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References