Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-DinJ
Location 637101..637656 Replicon chromosome
Accession NZ_CP113920
Organism Bifidobacterium sp. ESL0732

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OZX70_RS02215 Protein ID WP_277181637.1
Coordinates 637333..637656 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OZX70_RS02210 Protein ID WP_277181636.1
Coordinates 637101..637346 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX70_RS02195 (OZX70_02195) 632712..633335 + 624 WP_277182074.1 YigZ family protein -
OZX70_RS02200 (OZX70_02200) 633357..634052 + 696 WP_277181634.1 AbrB family transcriptional regulator -
OZX70_RS02205 (OZX70_02205) 635568..636521 + 954 WP_277181635.1 hypothetical protein -
OZX70_RS02210 (OZX70_02210) 637101..637346 + 246 WP_277181636.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX70_RS02215 (OZX70_02215) 637333..637656 + 324 WP_277181637.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OZX70_RS02220 (OZX70_02220) 637869..638318 + 450 WP_277143808.1 50S ribosomal protein L13 -
OZX70_RS02225 (OZX70_02225) 638340..638831 + 492 WP_277148890.1 30S ribosomal protein S9 -
OZX70_RS02230 (OZX70_02230) 638999..639397 + 399 WP_277182075.1 VOC family protein -
OZX70_RS02235 (OZX70_02235) 639875..642640 + 2766 WP_277181638.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-103)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-53)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11818.88 Da        Isoelectric Point: 9.6541

>T266165 WP_277181637.1 NZ_CP113920:637333-637656 [Bifidobacterium sp. ESL0732]
VRRGEIWTVLTDGYASKPRPVIIIQNDEVPDFQSVVMCLLTSYDAGDIATRVRIEPSSGNGLNKVSFAMTDKILSVERKV
LGRKVGVLEGKTMRDIDKKLMVVLGLV

Download         Length: 324 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8958.07 Da        Isoelectric Point: 6.2643

>AT266165 WP_277181636.1 NZ_CP113920:637101-637346 [Bifidobacterium sp. ESL0732]
MTTQLATRVDDQQAALFKRTAQKLGTTAADALRMFVAAFNDNQGFPYDVRLKSQAPEPFATEQEATDFASKMAGRLLSET
R

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References