Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 821644..822528 Replicon chromosome
Accession NZ_CP113918
Organism Bifidobacterium sp. ESL0769

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX72_RS03295 Protein ID WP_277158986.1
Coordinates 822031..822528 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX72_RS03290 Protein ID WP_277158985.1
Coordinates 821644..822018 (+) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX72_RS03260 (OZX72_03260) 817175..818077 + 903 WP_277159348.1 ABC transporter permease -
OZX72_RS03265 (OZX72_03265) 818080..818868 + 789 WP_277159349.1 ABC transporter ATP-binding protein -
OZX72_RS03270 (OZX72_03270) 818861..819646 + 786 WP_277158981.1 dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein -
OZX72_RS03275 (OZX72_03275) 819655..820647 - 993 WP_277158982.1 NAD(P)-dependent oxidoreductase -
OZX72_RS03280 (OZX72_03280) 820759..820962 - 204 WP_277158983.1 helix-turn-helix transcriptional regulator -
OZX72_RS03285 (OZX72_03285) 820949..821467 - 519 WP_277158984.1 hypothetical protein -
OZX72_RS03290 (OZX72_03290) 821644..822018 + 375 WP_277158985.1 damage-inducible protein J Antitoxin
OZX72_RS03295 (OZX72_03295) 822031..822528 + 498 WP_277158986.1 PIN domain-containing protein Toxin
OZX72_RS03300 (OZX72_03300) 822645..823268 + 624 WP_277158987.1 isochorismatase family protein -
OZX72_RS03305 (OZX72_03305) 823268..825268 + 2001 WP_277158988.1 DNA helicase RecQ -
OZX72_RS03310 (OZX72_03310) 825355..825825 + 471 WP_277158989.1 ASCH domain-containing protein -
OZX72_RS03315 (OZX72_03315) 825965..827296 + 1332 WP_277158990.1 HRDC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-142)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18515.34 Da        Isoelectric Point: 4.4090

>T266162 WP_277158986.1 NZ_CP113918:822031-822528 [Bifidobacterium sp. ESL0769]
MIEEKRVVFDTNVLLDYLLGWRSGNANAIQLLRVCLDSDVIKLLCISLSLKDVDYISRSSFKKQFANSESVVVQATVSNM
APKFGWHCVDDLLKIIAMVVAVDQVTCKNALKLWEVHPDYEDDLIIAASRQANADMVVTGDQDLIKHFPDLCVSVEDALK
QIEED

Download         Length: 498 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14199.97 Da        Isoelectric Point: 5.0638

>AT266162 WP_277158985.1 NZ_CP113918:821644-822018 [Bifidobacterium sp. ESL0769]
MGAVKEIVMSMVQMNVRIDSDVKDDVDEILKRKGKNPSSVVRELWDFIRDSGDTPDLRTKAEKANKEAEKQRRLKAIEDG
ATLWSRTLKEAGLSDDGQHPWANMSYKEMRDAAYEDVVDEYAHK

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References