Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/PIN(toxin)
Location 1596395..1597257 Replicon chromosome
Accession NZ_CP113917
Organism Bifidobacterium sp. ESL0775

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZX73_RS06095 Protein ID WP_277148541.1
Coordinates 1596395..1596892 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZX73_RS06100 Protein ID WP_277148544.1
Coordinates 1596907..1597257 (-) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX73_RS06080 (OZX73_06080) 1592118..1593434 - 1317 WP_277148535.1 HRDC domain-containing protein -
OZX73_RS06085 (OZX73_06085) 1593635..1595641 - 2007 WP_277148537.1 DNA helicase RecQ -
OZX73_RS06090 (OZX73_06090) 1595641..1596264 - 624 WP_277148539.1 isochorismatase family protein -
OZX73_RS06095 (OZX73_06095) 1596395..1596892 - 498 WP_277148541.1 PIN domain-containing protein Toxin
OZX73_RS06100 (OZX73_06100) 1596907..1597257 - 351 WP_277148544.1 damage-inducible protein J Antitoxin
OZX73_RS06105 (OZX73_06105) 1597396..1599204 - 1809 WP_277148546.1 alpha-glucosidase -
OZX73_RS06110 (OZX73_06110) 1599542..1599961 + 420 WP_277148548.1 hypothetical protein -
OZX73_RS06115 (OZX73_06115) 1599948..1600151 + 204 WP_277148550.1 helix-turn-helix transcriptional regulator -
OZX73_RS06120 (OZX73_06120) 1600260..1601252 + 993 WP_277148551.1 D-2-hydroxyacid dehydrogenase family protein -
OZX73_RS06125 (OZX73_06125) 1601261..1602049 - 789 WP_277148553.1 dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-142)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18493.27 Da        Isoelectric Point: 4.4090

>T266160 WP_277148541.1 NZ_CP113917:c1596892-1596395 [Bifidobacterium sp. ESL0775]
MIEEKRVVFDTNVLLDYLLGWRSGNANAMQLLRACLDSDVIKLLCISLSLKDVDYISRSSFKKQFANSESVVVQATVSNM
APKFGWHCVDDLLKLIAMVVAVDQSTCKNALKLWEVHPDYEDDLIIAASRQANADMVVTGDQDLIKHFPDLCVSVEDALK
QIEED

Download         Length: 498 bp

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 13480.04 Da        Isoelectric Point: 4.6379

>AT266160 WP_277148544.1 NZ_CP113917:c1597257-1596907 [Bifidobacterium sp. ESL0775]
MSMVQMNVRIDADLKDDVDEILKRRGKNPSSVVRELWDFIKDYGDTPDLQTKAEKADREAEKQRRLKAMEDGATLWSRTL
KEAGLSDDGEHPWANMTYKEMRDAAYEDVVDEYAHK

Download         Length: 351 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References