Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 256957..257522 Replicon chromosome
Accession NZ_CP113917
Organism Bifidobacterium sp. ESL0775

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OZX73_RS00750 Protein ID WP_277149712.1
Coordinates 256957..257214 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag OZX73_RS00755 Protein ID WP_277149714.1
Coordinates 257211..257522 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX73_RS00725 (OZX73_00725) 252281..252439 - 159 WP_277149702.1 hypothetical protein -
OZX73_RS00730 (OZX73_00730) 252480..253391 - 912 WP_277149704.1 GAF domain-containing protein -
OZX73_RS00735 (OZX73_00735) 253388..253903 - 516 WP_277149706.1 hypothetical protein -
OZX73_RS00740 (OZX73_00740) 254211..255491 + 1281 WP_277149708.1 alpha/beta hydrolase -
OZX73_RS00745 (OZX73_00745) 255619..256830 + 1212 WP_277149710.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
OZX73_RS00750 (OZX73_00750) 256957..257214 - 258 WP_277149712.1 Txe/YoeB family addiction module toxin Toxin
OZX73_RS00755 (OZX73_00755) 257211..257522 - 312 WP_277149714.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OZX73_RS00760 (OZX73_00760) 257674..258672 - 999 WP_277149716.1 2-dehydropantoate 2-reductase -
OZX73_RS00765 (OZX73_00765) 258778..259089 - 312 WP_277149718.1 hypothetical protein -
OZX73_RS00770 (OZX73_00770) 259156..260160 - 1005 WP_277149720.1 ketopantoate reductase family protein -
OZX73_RS00775 (OZX73_00775) 260523..261095 + 573 WP_277149722.1 TIGR00730 family Rossman fold protein -
OZX73_RS00780 (OZX73_00780) 261724..261888 + 165 WP_277149724.1 hypothetical protein -
OZX73_RS00785 (OZX73_00785) 261889..262494 - 606 WP_277149726.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10118.46 Da        Isoelectric Point: 8.0307

>T266158 WP_277149712.1 NZ_CP113917:c257214-256957 [Bifidobacterium sp. ESL0775]
MNLAWTEDGWNDYLHWQRQDKKTLRRINTLITNMLRTPFEGIGKPEPLKWGLEGAWSRRIDSANRIIYTVSDNEICILSA
RNHYE

Download         Length: 258 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11765.17 Da        Isoelectric Point: 4.8236

>AT266158 WP_277149714.1 NZ_CP113917:c257522-257211 [Bifidobacterium sp. ESL0775]
MVQAVAYSNFRKDLKSYMRKVNEDADLLLITNPNPDDNVVVMSADDYESLMETMRIYQNPYLHKKITKGLQQVRDGSVRQ
YSLIDPDAEDSYSSPAKRNGTEG

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References