Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1113498..1114031 Replicon chromosome
Accession NZ_CP113916
Organism Lactobacillus sp. ESL0785

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OZY43_RS05290 Protein ID WP_277164038.1
Coordinates 1113759..1114031 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OZY43_RS05285 Protein ID WP_277164037.1
Coordinates 1113498..1113755 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZY43_RS05265 (OZY43_05265) 1109981..1110127 - 147 Protein_997 D-2-hydroxyacid dehydrogenase -
OZY43_RS05270 (OZY43_05270) 1111044..1112093 + 1050 WP_277164034.1 restriction endonuclease subunit S -
OZY43_RS05275 (OZY43_05275) 1112256..1112417 - 162 WP_277164035.1 hypothetical protein -
OZY43_RS05280 (OZY43_05280) 1112434..1113354 - 921 WP_277164036.1 site-specific integrase -
OZY43_RS05285 (OZY43_05285) 1113498..1113755 + 258 WP_277164037.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZY43_RS05290 (OZY43_05290) 1113759..1114031 + 273 WP_277164038.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZY43_RS05295 (OZY43_05295) 1114094..1115302 - 1209 WP_277164039.1 restriction endonuclease subunit S -
OZY43_RS05300 (OZY43_05300) 1115295..1116950 - 1656 WP_277164040.1 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10505.31 Da        Isoelectric Point: 9.9839

>T266157 WP_277164038.1 NZ_CP113916:1113759-1114031 [Lactobacillus sp. ESL0785]
MLNIKVTAKFRKDVKRCNKQGLPMTQLKLVIHELEQNHVLPSNYKNHALDGTYSNYLECHIKPDWLLIYQITQTTLALIR
TGSHAELFKK

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9749.08 Da        Isoelectric Point: 4.6135

>AT266157 WP_277164037.1 NZ_CP113916:1113498-1113755 [Lactobacillus sp. ESL0785]
MNKTLQARMDGKLMDEAEGILKDLGLNRSTALKIFYQQIVWNNGLPFAVKKPEIPNEETLDAMHEDLSKTKTYDNSDELW
HDLGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References