Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 4711923..4712742 Replicon chromosome
Accession NZ_CP113904
Organism Klebsiella michiganensis strain PS_Koxy4

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag F0A14_RS22335 Protein ID WP_004110819.1
Coordinates 4712485..4712742 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag F0A14_RS22330 Protein ID WP_182094342.1
Coordinates 4711923..4712474 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0A14_RS22310 (F0A14_022310) 4707293..4708690 + 1398 WP_032718963.1 MFS transporter -
F0A14_RS22315 (F0A14_022315) 4708812..4710152 + 1341 WP_014228059.1 carbohydrate porin -
F0A14_RS22320 (F0A14_022320) 4710277..4711023 - 747 WP_228304563.1 class I SAM-dependent methyltransferase -
F0A14_RS22325 (F0A14_022325) 4711447..4711809 - 363 Protein_4395 class I SAM-dependent methyltransferase -
F0A14_RS22330 (F0A14_022330) 4711923..4712474 - 552 WP_182094342.1 N-acetyltransferase Antitoxin
F0A14_RS22335 (F0A14_022335) 4712485..4712742 - 258 WP_004110819.1 YjhX family toxin Toxin
F0A14_RS22340 (F0A14_022340) 4713418..4714602 + 1185 WP_014228054.1 mannonate dehydratase -
F0A14_RS22345 (F0A14_022345) 4714676..4716151 + 1476 WP_014228053.1 fructuronate reductase -
F0A14_RS22350 (F0A14_022350) 4716290..4717066 + 777 WP_004847986.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T266145 WP_004110819.1 NZ_CP113904:c4712742-4712485 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19931.79 Da        Isoelectric Point: 6.3260

>AT266145 WP_182094342.1 NZ_CP113904:c4712474-4711923 [Klebsiella michiganensis]
MTNHSFTIHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGELIRHGIEQLKAMGSQMVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPAAHKACWMLQPISS
QPLGRTGQIQCALALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References